The medical properties of metals have been explored for centuries in traditional medicine for
the treatment of infections and diseases and still practiced to date. Platinum-based drugs are …

Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

Obesity has been linked to the increased risk and aggressiveness of many types of
carcinoma. A state of chronic inflammation in adipose tissue (AT), resulting in genotoxic …

There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Photodynamic therapy and adipose browning induction are two promising approaches to
reverse obesity. The former strategy acts rapidly and locally, whereas the latter has a more …

Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Developing CAR T cells for acute myeloid leukemia (AML) has been hampered by a paucity
of targets that are expressed on AML blasts and not on hematopoietic progenitor cells …

Our understanding of adipose tissue biology has progressed rapidly since the turn of the
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …