Neurodegenerative disease and cAMP signaling dynamics

Papaverine, a phosphodiesterase 10A inhibitor, ameliorates quinolinic acid-induced synaptotoxicity in human cortical neurons

A Bhat, V Tan, B Heng, S Chow, S Basappa… - Neurotoxicity …, 2021 - Springer
Abstract Phosphodiesterase-10A (PDE10A) hydrolyse the secondary messengers cGMP
and cAMP, two molecules playing important roles in neurodevelopment and brain functions …
被引用次数：19 相关文章 所有 7 个版本
[PDF] biorxiv.org

Inhibition of phosphodiesterase-10A by Papaverine protects human cortical neurons from quinolinic acid induced oxidative stress and synaptic proteins alterations

A Bhat, V Tan, B Heng, MM Essa, SB Chidambaram… - bioRxiv, 2020 - biorxiv.org
Abstract Phosphodi esterase-10A (PDE10A) hydrolyse the secondary messengers cGMP
and cAMP which play critical role in neurodevelopment and brain functions. PDE10A is …
相关文章 所有 4 个版本