Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
Psychedelics
DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …
perception and mood and affect numerous cognitive processes. They are generally …
The effects of serotonin in immune cells
N Herr, C Bode, D Duerschmied - Frontiers in cardiovascular …, 2017 - frontiersin.org
Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a
peripheral hormone. Most of the body's serotonin is circulating in the bloodstream …
peripheral hormone. Most of the body's serotonin is circulating in the bloodstream …
Pivotal mental states
A Brouwer, RL Carhart-Harris - Journal of …, 2021 - journals.sagepub.com
This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …
plastic state aiding rapid and deep learning that can mediate psychological transformation …
Psychedelics as medicines: an emerging new paradigm
DE Nichols, MW Johnson… - Clinical Pharmacology & …, 2017 - Wiley Online Library
Scientific interest in serotonergic psychedelics (eg, psilocybin and LSD; 5‐HT2A receptor
agonists) has dramatically increased within the last decade. Clinical studies administering …
agonists) has dramatically increased within the last decade. Clinical studies administering …
Critical neurotransmitters in the neuroimmune network
TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …
express an extensive network of cell communication modes, including a vast repertoire of …
Microdosing psychedelics: More questions than answers? An overview and suggestions for future research
KPC Kuypers, L Ng, D Erritzoe… - Journal of …, 2019 - journals.sagepub.com
Background: In the past few years, the issue of 'microdosing'psychedelics has been openly
discussed in the public arena where claims have been made about their positive effect on …
discussed in the public arena where claims have been made about their positive effect on …
Psychedelics as anti-inflammatory agents
TW Flanagan, CD Nichols - International Review of Psychiatry, 2018 - Taylor & Francis
Abstract Serotonin (5-hydroxytryptamine, 5-HT) 2A receptor agonists have recently emerged
as promising new treatment options for a variety of disorders. The recent success of these …
as promising new treatment options for a variety of disorders. The recent success of these …
Reflex control of immunity
KJ Tracey - Nature Reviews Immunology, 2009 - nature.com
Inflammation can cause damage and even death. What controls this primitive and potentially
lethal innate immune response to injury and infection? Molecular and neurophysiological …
lethal innate immune response to injury and infection? Molecular and neurophysiological …
Current perspectives on psychedelic therapy: use of serotonergic hallucinogens in clinical interventions
A Garcia-Romeu, WA Richards - International Review of Psychiatry, 2018 - Taylor & Francis
Humans have used serotonergic hallucinogens (ie psychedelics) for spiritual, ceremonial,
and recreational purposes for thousands of years, but their administration as part of a …
and recreational purposes for thousands of years, but their administration as part of a …