Brodmann has pioneered structural brain mapping. He considered functional and
pathological criteria for defining cortical areas in addition to cytoarchitecture. Starting from …

Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …

Rapid eye movement (REM) sleep is accompanied by intense cortical activity, underlying its
wake-like electroencephalogram. The neural activity inducing REM sleep is thought to …

Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …

Defining cell types requires integrating diverse single-cell measurements from multiple
experiments and biological contexts. To flexibly model single-cell datasets, we developed …

The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …

Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …

Nervous systems are composed of various cell types, but the extent of cell type diversity is
poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual …

The mammalian brain contains diverse neuronal types, yet we lack single-cell epigenomic
assays that are able to identify and characterize them. DNA methylation is a stable …