Executive functions, or cognitive control, are higher-order cognitive functions needed for
adaptive goal-directed behaviours and are significantly impaired in majority of …

Dopamine is an important neurotransmitter that plays a key role in neuropsychiatric illness.
Sex differences in dopaminergic signaling have been acknowledged for decades and have …

Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

The faster a drug enters the brain, the greater its addictive potential, yet the brain circuits
underlying the rate dependency to drug reward remain unresolved. With simultaneous PET …

The synthetic opioid fentanyl is a major contributor to the current opioid addiction crisis. We
report that claustral neurons projecting to the frontal cortex limit oral fentanyl self …

Substance use disorders are associated with neuroimaging abnormalities, but results are
heterogeneous across studies and vary across substances, and the causal interpretation of …

An understanding of the neurocognitive profile underlying the use of social networking sites
(SNSs) can help inform decisions about the classification of problematic SNS use as an …

Human neuroimaging has demonstrated the existence of large-scale functional networks in
the cerebral cortex consisting of topographically distant brain regions with functionally …

Background: Drug addiction is a complex brain disorder that is characterized by craving,
withdrawal, and relapse, which can be perpetuated by social stress. Stemming from an …

Most addiction research has focused on reward-and impulsivity-related neurocircuitry.
However, the impact of the withdrawal/negative affect stage in the addiction cycle has been …