The interplay between m6A RNA methylation and noncoding RNA in cancer
S Ma, C Chen, X Ji, J Liu, Q Zhou, G Wang… - Journal of hematology & …, 2019 - Springer
Abstract N6-methyladenosine (m6A) methylation, one of the most common RNA
modifications, has been reported to execute important functions that affect normal life …
modifications, has been reported to execute important functions that affect normal life …
Regulation of microRNA function in animals
LFR Gebert, IJ MacRae - Nature reviews Molecular cell biology, 2019 - nature.com
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …
key regulators of biological processes in animals. These small RNAs form complex networks …
Structure of the human DICER–pre-miRNA complex in a dicing state
Dicer has a key role in small RNA biogenesis, processing double-stranded RNAs
(dsRNAs),. Human DICER (hDICER, also known as DICER1) is specialized for cleaving …
(dsRNAs),. Human DICER (hDICER, also known as DICER1) is specialized for cleaving …
microRNA strand selection: Unwinding the rules
Abstract microRNAs (miRNAs) play a central role in the regulation of gene expression by
targeting specific mRNAs for degradation or translational repression. Each miRNA is post …
targeting specific mRNAs for degradation or translational repression. Each miRNA is post …
Double-stranded RNA sensors and modulators in innate immunity
S Hur - Annual review of immunology, 2019 - annualreviews.org
Detection of double-stranded RNAs (dsRNAs) is a central mechanism of innate immune
defense in many organisms. We here discuss several families of dsRNA-binding proteins …
defense in many organisms. We here discuss several families of dsRNA-binding proteins …
MicroRNA biogenesis pathways in cancer
S Lin, RI Gregory - Nature reviews cancer, 2015 - nature.com
MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …
Systems and synthetic microRNA biology: from biogenesis to disease pathogenesis
H Matsuyama, HI Suzuki - International journal of molecular sciences, 2019 - mdpi.com
MicroRNAs (miRNAs) are approximately 22-nucleotide-long, small non-coding RNAs that
post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple …
post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple …
RISC assembly: Coordination between small RNAs and Argonaute proteins
H Kobayashi, Y Tomari - Biochimica et Biophysica Acta (BBA)-Gene …, 2016 - Elsevier
Non-coding RNAs generally form ribonucleoprotein (RNP) complexes with their partner
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …
[HTML][HTML] Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
Protein kinase R (PKR) is an immune response protein that becomes activated by double-
stranded RNAs (dsRNAs). PKR overactivation is associated with degenerative diseases with …
stranded RNAs (dsRNAs). PKR overactivation is associated with degenerative diseases with …
Circulating microRNAs as potential biomarkers of infectious disease
CN Correia, NC Nalpas, KE McLoughlin… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that
regulate a wide range of biological processes by post-transcriptionally regulating gene …
regulate a wide range of biological processes by post-transcriptionally regulating gene …