Irisin in metabolic diseases

SA Polyzos, AD Anastasilakis, ZA Efstathiadou… - Endocrine, 2018 - Springer
Introduction Irisin is a myokine/adipokine induced by the exercise in mice and humans,
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …

[HTML][HTML] The adipokine network in rheumatic joint diseases

M Carrión, KW Frommer, S Pérez-García… - International journal of …, 2019 - mdpi.com
Rheumatic diseases encompass a diverse group of chronic disorders that commonly affect
musculoskeletal structures. Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two …

[HTML][HTML] Role of omentin, vaspin, cardiotrophin-1, TWEAK and NOV/CCN3 in obesity and diabetes development

X Escoté, S Gómez-Zorita, M López-Yoldi… - International journal of …, 2017 - mdpi.com
Adipose tissue releases bioactive mediators called adipokines. This review focuses on the
effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of …

[HTML][HTML] Irisin and autophagy: first update

M Pesce, P Ballerini, T Paolucci, I Puca… - International journal of …, 2020 - mdpi.com
Aging and sedentary life style are considered independent risk factors for many disorders.
Under these conditions, accumulation of dysfunctional and damaged cellular proteins and …

[HTML][HTML] Omentin-1 in diabetes mellitus: A systematic review and meta-analysis

X Pan, AC Kaminga, SW Wen, K Acheampong, A Liu - PLoS One, 2019 - journals.plos.org
Objective Previous studies found inconsistent results on the relationship between diabetes
mellitus and concentrations of omentin-1. This study performed a systematic review and …

Circulating nesfatin‐1 levels and type 2 diabetes: A systematic review and meta‐analysis

T Zhai, SZ Li, XT Fan, Z Tian, XQ Lu… - Journal of diabetes …, 2017 - Wiley Online Library
The role of nesfatin‐1 in glucose homeostasis has been investigated previously. However,
although numerous studies have examined the relationships between circulating nesfatin‐1 …

Fibroblast growth factor 21 in lipid metabolism and non-alcoholic fatty liver disease

X Su, Y Kong, D Peng - Clinica Chimica Acta, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in
several developed countries, ranging from simple non-alcoholic fatty liver (NAFL) to non …

[HTML][HTML] The variation and correlation of serum adiponectin, nesfatin-1, IL-6, and TNF-α levels in prediabetes

K Huang, Y Liang, Y Ma, J Wu, H Luo… - Frontiers in Endocrinology, 2022 - frontiersin.org
Background The variation and correlation among adiponectin, nesfatin-1, tumor necrosis
factor α (TNF-α), and interleukin 6 (IL-6), which may be involved in the development of the …

Fasting plasma glucose is a stronger predictor of diabetes than triglyceride–glucose index, triglycerides/high-density lipoprotein cholesterol, and homeostasis model …

M Tohidi, A Baghbani-Oskouei, NS Ahanchi, F Azizi… - Acta Diabetologica, 2018 - Springer
Aims To compare the impact of triglyceride–glucose index (TyG-index), the product of fasting
plasma glucose (FPG) and triglycerides (TG) with FPG, 2 h post-challenge plasma glucose …

Hepsin enhances liver metabolism and inhibits adipocyte browning in mice

S Li, J Peng, H Wang, W Zhang… - Proceedings of the …, 2020 - National Acad Sciences
Hepsin is a transmembrane serine protease primarily expressed in the liver. To date, the
physiological function of hepsin remains poorly defined. Here we report that hepsin-deficient …