Recent advances in the formulation of PLGA microparticles for controlled drug delivery

E Lagreca, V Onesto, C Di Natale, S La Manna… - Progress in …, 2020 - Springer
Polymeric microparticles (MPs) are recognized as very popular carriers to increase the
bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different …

PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

A review of microfluidic experimental designs for nanoparticle synthesis

AG Niculescu, DE Mihaiescu… - International Journal of …, 2022 - mdpi.com
Microfluidics is defined as emerging science and technology based on precisely
manipulating fluids through miniaturized devices with micro-scale channels and chambers …

Recent advances in the design of microfluidic technologies for the manufacture of drug releasing particles

A Forigua, RL Kirsch, SM Willerth, KS Elvira - Journal of Controlled Release, 2021 - Elsevier
Drug releasing particles are valued for their ability to deliver therapeutics to targeted
locations and for their controllable release patterns. The development of microfluidic …

Recent progress in nucleic acid detection with CRISPR

FX Liu, JQ Cui, Z Wu, S Yao - Lab on a Chip, 2023 - pubs.rsc.org
Recent advances in CRISPR-based biotechnologies have greatly expanded our capabilities
to repurpose CRISPR for the development of molecular diagnostic systems. The key …

Droplet-based microfluidics for drug delivery applications

R Fan, J Wu, S Duan, L Jin, H Zhang, C Zhang… - International Journal of …, 2024 - Elsevier
The microfluidic method primainly utilizes two incompatible liquids as continuous phase and
dispersed phase respectively. It controls the formation of droplets by managing the …

Bridging the gap between fundamental research and product development of long acting injectable PLGA microspheres

X Li, Z Zhang, A Harris, L Yang - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
ABSTRACT Introduction Long-acting Injectable PLGA microspheres have gained more and
more interest and attention in the field of life cycle management of pharmaceutical products …

Practical quality attributes of polymeric microparticles with current understanding and future perspectives

R Bhujel, R Maharjan, NA Kim, SH Jeong - Journal of Drug Delivery …, 2021 - Elsevier
Polymeric microparticles are preferred over the non-polymeric one based on the market
trends and diverse conventional methods have been used to fabricate the polymeric …

Recent research and development of local anesthetic-loaded microspheres

Y Wei, Y Wu, K Wen, N Bazybek, G Ma - Journal of Materials Chemistry …, 2020 - pubs.rsc.org
Local anesthetic drugs are widely used in postoperative analgesia, local nerve block in
surgery, and in the therapy of chronic pain. Due to their short half-time, a single …

High-aspect-ratio microfluidic channel with parallelogram cross-section for monodisperse droplet generation

H Ji, J Lee, J Park, J Kim, HS Kim, Y Cho - Biosensors, 2022 - mdpi.com
Droplet-based microfluidics has been widely used as a potent high-throughput platform due
to various advantages, such as a small volume of reagent consumption, massive production …