The zebrafish is a recent addition to animal models of human cancer, and studies using this
model are rapidly contributing major insights. Zebrafish develop cancer spontaneously, after …

Hematopoiesis is a complex process with a variety of different signaling pathways
influencing every step of blood cell formation from the earliest precursors to final …

Abstract The Zebrafish Model Organism Database (ZFIN; https://zfin. org) is the central
resource for genetic, genomic, and phenotypic data for zebrafish (Danio rerio) research …

The current preclinical pipeline for drug discovery can be cumbersome and costly, which
limits the number of compounds that can effectively be transitioned to use as therapies …

Background Deadenylation regulates RNA function and fate. Poly (A)-specific ribonuclease
(PARN) is a deadenylase that processes mRNAs and non-coding RNA. Little is known about …

Zebrafish (Danio rerio) is an excellent model to study a wide diversity of human cancers. In
this review, we provide an overview of the genetic and reverse genetic toolbox allowing the …

Emerging bio-contaminants such as viruses have affected health and environment settings
of every country. Viruses are the minuscule entities resulting in severe contagious diseases …

Transgenic approaches are instrumental for labeling and manipulating cells and cellular
machineries in vivo. Transgenes have traditionally been static entities that remained …

Zebrafish is an established model for the study of vertebrate development, and is especially
amenable for investigating hematopoiesis, where there is strong conservation of key …

The need for scalable strategies to probe the biological consequences of candidate cancer
genes has never been more pressing. The zebrafish, with its capacity for high-throughput …