Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Lung cancer is the leading cause of cancer-related death across the world. Unlike lung
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …

The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

Fibroblast growth factors (FGFs) and their receptors control a wide range of biological
functions, regulating cellular proliferation, survival, migration and differentiation. Although …

Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …

Fibroblast growth factors (FGFs) are small polypeptide growth factors, all of whom share in
common certain structural characteristics, and most of whom bind heparin avidly. Many …

Angiogenesis, or the formation of new blood vessels out of pre-existing capillaries, is a
sequence of events that is fundamental to many physiologic and pathologic processes such …

Fibroblast growth factors (FGFs) play important roles during fetal and embryonic
development. FGF-2 (basic FGF, bFGF) is widely expressed in the embryo and has been …

Fibroblast growth factor (FGF) signaling regulates cell proliferation, differentiation, survival,
angiogenesis, and wound healing. Compelling evidence for deregulated FGF signaling in …

Angiogenesis depends on the cooperation of growth factors and cell adhesion events.
Although αv integrins have been shown to play critical roles in angiogenesis, recent studies …