The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Neurodegenerative disorders, such as Alzheimer's disease, are a global public health
burden with poorly understood aetiology. Neuroinflammation and oxidative stress (OS) are …

Oxidative stress has been implicated in the pathogenesis of Alzheimer's disease (AD).
Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in …

Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

For a number of years, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases
(NOX) was synonymous with NOX2/gp91phox and was considered to be a peculiarity of …

Oxidative stress is a common denominator in the pathology of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral …

The goal of this review is to discuss how behavioral tests in mice relate to the pathological
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …

Oxidative stress occurs in a variety of disease settings and is strongly linked to the
development of neuron death and neuronal dysfunction. Cells are equipped with numerous …

Significance: There is increasing evidence that the generation of reactive oxygen species
(ROS) in the central nervous system (CNS) involves the NOX family of nicotinamide adenine …