Cancer incidence and mortality rates are increasing annually. Treatment with surgery,
chemotherapy and radiation therapy (RT) is unsatisfactory because many patients have …

The tumor microenvironment (TME) is shaped by dynamic metabolic and immune
interactions between precancerous and cancerous tumor cells and stromal cells like …

Pancreatic cancer (PC) is the primary cause of cancer-related mortality. Due to the absence
of reliable biomarkers for predicting prognosis or guiding treatment, there is an urgent need …

Background: Epigenetics studies heritable or inheritable mechanisms that regulate gene
expression rather than altering the DNA sequence. However, no research has investigated …

Background. Lymphocyte antigen 6 complex, locus E (LY6E) is abnormally expressed in
several cancers and is associated with poor outcomes. However, the biological role of LY6E …

Dendritic cells (DCs), a kind of specialized immune cells, play key roles in antitumor immune
response and promotion of innate and adaptive immune responses. Recently, many …

Prostate cancer (PCa) stands as a prominent contributor to morbidity and mortality among
males on a global scale. Cancer-associated fibroblasts (CAFs) are considered to be closely …

Introduction: The maturation faith of dendritic cells is restrained by the inflammatory
environment and cytokines, such as interleukin-6 and its downstream component. Therefore …

Antibody-drug conjugates (ADCs), combining the cytotoxicity of the drug payload with the
specificity of monoclonal antibodies, are one of the rapidly evolving classes of anti-cancer …

Dendritic cells (DCs) are professional antigen-presenting cells, which are resident or
proliferating in organs. Major histocompatibility complex (MHC) Class I and II on DCs in …