Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe
organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple
organs. A complex interaction of genetics, environment, and hormones leads to immune …

In November 2017, the Kidney Disease: Improving Global Outcomes (KDIGO) initiative
brought a diverse panel of experts in glomerular diseases together to discuss the 2012 …

Objective Current lupus nephritis (LN) treatments are effective in only 30% of patients,
emphasizing the need for novel therapeutic strategies. We undertook this study to develop …

Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Objective The goal of these studies is to discover novel urinary biomarkers of lupus nephritis
(LN). Methods Urine from systemic lupus erythematosus (SLE) patients was interrogated for …

The immune mechanisms that cause tissue injury in lupus nephritis have been challenging
to define. The advent of high-dimensional cellular analyses, such as single-cell RNA …

This study aimed to determine the expression of circRNAs in plasma from lupus nephritis
(LN) patients to identify novel biomarkers for LN screening. We initially performed microarray …

CD163 is a marker for alternatively activated macrophages, which have been implicated in
the pathogenesis of lupus nephritis (LN). In our preliminary screening of urine proteins in …

Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical
manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more …