Integrated analysis of multi-omics data for the discovery of biomarkers and therapeutic targets for colorectal cancer
N Zafari, P Bathaei, M Velayati… - Computers in Biology …, 2023 - Elsevier
The considerable burden of colorectal cancer and the rising trend in young adults
emphasize the necessity of understanding its underlying mechanisms, providing new …
emphasize the necessity of understanding its underlying mechanisms, providing new …
GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathway
F Lu, S Chen, W Shi, X Su, H Wu, M Liu - Plos one, 2022 - journals.plos.org
In this study, we analyzed GPC family genes in colorectal cancer (CRC) and the possible
mechanism of action of GPC1 in CRC. CRC patient data were extracted from The Cancer …
mechanism of action of GPC1 in CRC. CRC patient data were extracted from The Cancer …
RAB21 controls autophagy and cellular energy homeostasis by regulating retromer-mediated recycling of SLC2A1/GLUT1
Y Pei, S Lv, Y Shi, J Jia, M Ma, H Han, R Zhang, J Tan… - Autophagy, 2023 - Taylor & Francis
The endosomal system maintains cellular homeostasis by coordinating multiple vesicular
trafficking events, and the retromer complex plays a critical role in endosomal cargo …
trafficking events, and the retromer complex plays a critical role in endosomal cargo …
STAT3-mediated ferroptosis is involved in sepsis-associated acute respiratory distress syndrome
S Lin, J Yan, W Wang, L Luo - Inflammation, 2024 - Springer
Sepsis-induced acute respiratory distress syndrome (ARDS) poses a grave danger to life,
resulting from sepsis-induced multi-organ failure. Although ferroptosis, a form of iron …
resulting from sepsis-induced multi-organ failure. Although ferroptosis, a form of iron …
Large-scale external validation and meta-analysis of gene methylation biomarkers in tumor tissue for colorectal cancer prognosis
T Yuan, D Wankhede, D Edelmann, JN Kather… - …, 2024 - thelancet.com
Background DNA methylation biomarkers in colorectal cancer (CRC) tissue hold potential as
prognostic indicators. However, individual studies have yielded heterogeneous results, and …
prognostic indicators. However, individual studies have yielded heterogeneous results, and …
A novel inflammatory lncRNAs prognostic signature for predicting the prognosis of low-grade glioma patients
Z Xiang, X Chen, Q Lv, X Peng - Frontiers in Genetics, 2021 - frontiersin.org
Background As immunotherapy has received attention as new treatments for brain cancer,
the role of inflammation in the process of glioma is of particular importance. Increasing …
the role of inflammation in the process of glioma is of particular importance. Increasing …
Identification and validation of an inflammation-related lncRNAs signature for improving outcomes of patients in colorectal cancer
M Huang, Y Ye, Y Chen, J Zhu, L Xu, W Cheng… - Frontiers in …, 2022 - frontiersin.org
Background: Colorectal cancer is the fourth most deadly cancer worldwide. Although current
treatment regimens have prolonged the survival of patients, the prognosis is still …
treatment regimens have prolonged the survival of patients, the prognosis is still …
Inflammation-related genes serve as prognostic biomarkers and involve in immunosuppressive microenvironment to promote gastric cancer progression
Y Wei, L Gao, X Yang, X Xiang, C Yi - Frontiers in Medicine, 2022 - frontiersin.org
Gastric cancer (GC) is a typical inflammatory-related malignant tumor which is closely
related to helicobacter pylori infection. Tumor inflammatory microenvironment plays a crucial …
related to helicobacter pylori infection. Tumor inflammatory microenvironment plays a crucial …
[HTML][HTML] Combined detection of preoperative neutrophil to lymphocyte ratio and interleukin-6 as an independent prognostic factor for patients with non-metastatic …
Z Yang, Y Li, K Zhang, X Deng, S Yang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background This study sought to explore the value of the neutrophil to lymphocyte ratio
(NLR) and interleukin-6 (IL-6) in predicting the prognosis of patients with non-metastatic …
(NLR) and interleukin-6 (IL-6) in predicting the prognosis of patients with non-metastatic …