Neurobiological interactions between stress and the endocannabinoid system
Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …
many neurobehavioral processes. A growing body of work indicates that the …
[HTML][HTML] The transition of acute postoperative pain to chronic pain: an integrative overview of research on mechanisms
CR Chapman, CJ Vierck - The Journal of pain, 2017 - Elsevier
The nature of the transition from acute to chronic pain still eludes explanation, but chronic
pain resulting from surgery provides a natural experiment that invites clinical …
pain resulting from surgery provides a natural experiment that invites clinical …
The cannabinoid system and pain
Chronic pain states are highly prevalent and yet poorly controlled by currently available
analgesics, representing an enormous clinical, societal, and economic burden. Existing pain …
analgesics, representing an enormous clinical, societal, and economic burden. Existing pain …
Cannabinoids and pain: sites and mechanisms of action
K Starowicz, DP Finn - Advances in Pharmacology, 2017 - Elsevier
The endocannabinoid system, consisting of the cannabinoid 1 receptor (CB 1 R) and
cannabinoid 2 receptor (CB 2 R), endogenous cannabinoid ligands (endocannabinoids) …
cannabinoid 2 receptor (CB 2 R), endogenous cannabinoid ligands (endocannabinoids) …
Alterations in the endocannabinoid system in the rat valproic acid model of autism
The endocannabinoid system plays a crucial role in regulating emotionality and social
behaviour, however it is unknown whether this system plays a role in symptoms associated …
behaviour, however it is unknown whether this system plays a role in symptoms associated …
Sex‐dependent effects of endocannabinoid modulation of conditioned fear extinction in rats
M Morena, AS Nastase, A Santori… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Women are twice as likely as men to develop post‐traumatic
stress disorder (PTSD) making the search for biological mechanisms underlying these …
stress disorder (PTSD) making the search for biological mechanisms underlying these …
Differential upregulation of the cannabinoid CB2 receptor in neurotoxic and inflammation-driven rat models of Parkinson's disease
The cannabinoid CB 2 receptor has recently emerged as a potential anti-inflammatory target
to break the self-sustaining cycle of neuroinflammation and neurodegeneration that is …
to break the self-sustaining cycle of neuroinflammation and neurodegeneration that is …
Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids
A Luchicchi, M Pistis - Molecular neurobiology, 2012 - Springer
Since the discovery of endocannabinoids and their receptors, two major members of the
endocannabinoid family, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), have been …
endocannabinoid family, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), have been …
Mechanisms of placebo analgesia: a dual-process model informed by insights from cross-species comparisons
Placebo treatments are pharmacologically inert, but are known to alleviate symptoms across
a variety of clinical conditions. Associative learning and cognitive expectations both play …
a variety of clinical conditions. Associative learning and cognitive expectations both play …
Endocannabinoids, endocannabinoid-like compounds and cortisone in head hair of health care workers as markers of stress and resilience during the early COVID …
I Biener, TT Mueller, J Lin, H Bao, J Steffen… - Translational …, 2024 - nature.com
The pandemic caused by SARS-CoV-2 impacted health systems globally, creating
increased workload and mental stress upon health care workers (HCW). During the first …
increased workload and mental stress upon health care workers (HCW). During the first …