T cell epitope predictions

B Peters, M Nielsen, A Sette - Annual Review of Immunology, 2020 - annualreviews.org
Throughout the body, T cells monitor MHC-bound ligands expressed on the surface of
essentially all cell types. MHC ligands that trigger a T cell immune response are referred to …

[HTML][HTML] Antigen processing and presentation in cancer immunotherapy

MY Lee, JW Jeon, C Sievers… - Journal for immunotherapy …, 2020 - ncbi.nlm.nih.gov
Background Knowledge about and identification of T cell tumor antigens may inform the
development of T cell receptor-engineered adoptive cell transfer or personalized cancer …

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

K Falk, O Rötzschke, S Stevanovié, G Jung… - Nature, 1991 - nature.com
The crystal structures of major histocompatibility complex (MHC) molecules contain a groove
occupied by heterogeneous material thought to represent peptides central to immune …

DNASTAR's Lasergene sequence analysis software

TG Burland - Bioinformatics methods and protocols, 1999 - Springer
DNASTAR’s Lasergene Sequence Analysis Software | SpringerLink Skip to main content
Advertisement SpringerLink Account Menu Find a journal Publish with us Search Cart Book …

T-cell epitope vaccine design by immunoinformatics

A Patronov, I Doytchinova - Open biology, 2013 - royalsocietypublishing.org
Vaccination is generally considered to be the most effective method of preventing infectious
diseases. All vaccinations work by presenting a foreign antigen to the immune system in …

Reliable prediction of T‐cell epitopes using neural networks with novel sequence representations

M Nielsen, C Lundegaard, P Worning… - Protein …, 2003 - Wiley Online Library
In this paper we describe an improved neural network method to predict T‐cell class I
epitopes. A novel input representation has been developed consisting of a combination of …

MHC ligands and peptide motifs: first listing

HG Rammensee, T Friede, S Stevanović - Immunogenetics, 1995 - Springer
The purpose of this article is to provide a compendium of major histocompatibility complex
(MHC) peptide motifs and MHC ligands known to date, together with a discussion of the …

NetMHCpan, a Method for Quantitative Predictions of Peptide Binding to Any HLA-A and -B Locus Protein of Known Sequence

M Nielsen, C Lundegaard, T Blicher, K Lamberth… - PloS one, 2007 - journals.plos.org
Background Binding of peptides to Major Histocompatibility Complex (MHC) molecules is
the single most selective step in the recognition of pathogens by the cellular immune system …

Several common HLA-DR types share largely overlapping peptide binding repertoires

S Southwood, J Sidney, A Kondo… - The Journal of …, 1998 - journals.aai.org
The peptide binding specificities of HLA-DRB1* 0401, DRB1* 0101, and DRB1* 0701 have
been analyzed by the use of large collections of synthetic peptides corresponding to …

The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteins

Y Fang, EJ Snijder - Virus research, 2010 - Elsevier
Our knowledge about the structure and function of the nonstructural proteins (nsps) encoded
by the arterivirus replicase gene has advanced in recent years. The continued …