Colorectal cancer screening: recommendations for physicians and patients from the US Multi-Society Task Force on Colorectal Cancer

DK Rex, CR Boland, JA Dominitz, FM Giardiello… - Gastroenterology, 2017 - Elsevier
This document updates the colorectal cancer (CRC) screening recommendations of the US
Multi-Society Task Force of Colorectal Cancer (MSTF), which represents the American …

Terminology, molecular features, epidemiology, and management of serrated colorectal neoplasia

SD Crockett, ID Nagtegaal - Gastroenterology, 2019 - Elsevier
In addition to the adenoma to carcinoma sequence, colorectal carcinogenesis can occur via
the serrated pathway. Studies have focused on clarification of categories and molecular …

Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells

U Testa, E Pelosi, G Castelli - Medical Sciences, 2018 - mdpi.com
Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

Emerging trends in colorectal cancer: Dysregulated signaling pathways

R Ahmad, JK Singh, A Wunnava… - International …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

Piecemeal cold snare polypectomy versus conventional endoscopic mucosal resection for large sessile serrated lesions: a retrospective comparison across two …

WA Van Hattem, N Shahidi, S Vosko, I Hartley, K Britto… - Gut, 2021 - gut.bmj.com
Objective Large (≥ 20 mm) sessile serrated lesions (L-SSL) are premalignant lesions that
require endoscopic removal. Endoscopic mucosal resection (EMR) is the existing standard …

Risk stratification for covert invasive cancer among patients referred for colonic endoscopic mucosal resection: a large multicenter cohort

NG Burgess, LF Hourigan, SA Zanati, GJ Brown… - Gastroenterology, 2017 - Elsevier
Background & Aims Among patients with large colorectal sessile polyps or laterally
spreading lesions, it is important to identify those at risk for submucosal invasive cancer …

Narrow-band imaging for detection of neoplasia at colonoscopy: a meta-analysis of data from individual patients in randomized controlled trials

NSS Atkinson, S Ket, P Bassett, D Aponte, S De Aguiar… - Gastroenterology, 2019 - Elsevier
Background & Aims Adenoma detection rate (ADR) is an important quality assurance
measure for colonoscopy. Some studies suggest that narrow-band imaging (NBI) may be …

Integrative analysis of exogenous, endogenous, tumour and immune factors for precision medicine

S Ogino, JA Nowak, T Hamada, AI Phipps, U Peters… - Gut, 2018 - gut.bmj.com
Immunotherapy strategies targeting immune checkpoints such as the CTLA4 and CD274
(programmed cell death 1 ligand 1, PD-L1)/PDCD1 (programmed cell death 1, PD-1) T-cell …

[HTML][HTML] An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas

RK Pai, M Bettington, A Srivastava, C Rosty - Modern Pathology, 2019 - Elsevier
Our understanding of serrated colorectal polyps has increased dramatically over the past
two decades and has led to a modern classification scheme for these lesions. Sessile …

The 2019 World Health Organization Classification of appendiceal, colorectal and anal canal tumours: an update and critical assessment

M Ahadi, A Sokolova, I Brown, A Chou, AJ Gill - Pathology, 2021 - Elsevier
The recently published 5th edition 2019 World Health Organization (WHO) Classification of
Tumours of the Digestive System brings significant changes from the 2010 4th edition. An …