Polymer-based wound dressing materials loaded with bioactive agents: Potential materials for the treatment of diabetic wounds

S Alven, S Peter, Z Mbese, BA Aderibigbe - Polymers, 2022 - mdpi.com
Diabetic wounds are severe injuries that are common in patients that suffer from diabetes.
Most of the presently employed wound dressing scaffolds are inappropriate for treating …

Electrospinning of natural polymers for the production of nanofibres for wound healing applications

ADJ Bombin, NJ Dunne, HO McCarthy - Materials Science and …, 2020 - Elsevier
Wound healing is a highly regulated process composed of four overlapping phases:(1)
coagulation/haemostasis,(2) inflammation,(3) proliferation and (4) remodelling …

Ongoing clinical trials of nonviral siRNA therapeutics

EA Narasipura, R VanKeulen-Miller, Y Ma… - Bioconjugate …, 2023 - ACS Publications
Short interfering RNAs (siRNA) are a powerful class of genetic medicines whose clinical
translation can be hindered by their suboptimal delivery properties in vivo. Here, we provide …

[HTML][HTML] Polysaccharide electrospun nanofibers for wound healing applications

G Tan, L Wang, W Pan, K Chen - International Journal of …, 2022 - ncbi.nlm.nih.gov
As a type of biological macromolecule, natural polysaccharides have been widely used in
wound healing due to their low toxicity, good biocompatibility, degradability and …

Electrospun nanofiber/hydrogel composite materials and their tissue engineering applications

M Zhang, S Xu, R Wang, Y Che, C Han, W Feng… - Journal of Materials …, 2023 - Elsevier
Electrospun nanofiber/hydrogel composites combine the excellent biochemical properties of
hydrogel with the biomimetic nature of electrospun fibers, and have attracted widespread …

1D, 2D, and 3D scaffolds promoting angiogenesis for enhanced wound healing

Y Guo, J Huang, Y Fang, H Huang, J Wu - Chemical Engineering Journal, 2022 - Elsevier
The formation of blood vessels, also known as angiogenesis, is important for skin wound
healing. To accelerate this process, many technologies have emerged in the field of tissue …

Research progress, models and simulation of electrospinning technology: A review

Y Guo, X Wang, Y Shen, K Dong, L Shen… - Journal of Materials …, 2022 - Springer
In recent years, nanomaterials have aroused extensive research interest in the world's
material science community. Electrospinning has the advantages of wide range of available …

[HTML][HTML] Applications and developments of gene therapy drug delivery systems for genetic diseases

X Pan, H Veroniaina, N Su, K Sha, F Jiang… - Asian journal of …, 2021 - Elsevier
Genetic diseases seriously threaten human health and have always been one of the
refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA …

New insights into balancing wound healing and scarless skin repair

S Zhou, M Xie, J Su, B Cai, J Li… - Journal of Tissue …, 2023 - journals.sagepub.com
Scars caused by skin injuries after burns, wounds, abrasions and operations have serious
physical and psychological effects on patients. In recent years, the research of scar free …

Functionalized antimicrobial nanofibers: Design criteria and recent advances

N Hamdan, A Yamin, SA Hamid, WKWA Khodir… - Journal of functional …, 2021 - mdpi.com
The rise of antibiotic resistance has become a major threat to human health and it is
spreading globally. It can cause common infectious diseases to be difficult to treat and leads …