Lab-on-a-chip models of the blood–brain barrier: Evolution, problems, perspectives

MA Deli, G Porkoláb, A Kincses, M Mészáros… - Lab on a Chip, 2024 - pubs.rsc.org
A great progress has been made in the development and use of lab-on-a-chip devices to
model and study the blood–brain barrier (BBB) in the last decade. We present the main …

Generation of hiPSC-derived brain microvascular endothelial cells using a combination of directed differentiation and transcriptional reprogramming strategies

A Cui, R Patel, P Bosco, U Akcan, E Richters… - bioRxiv, 2024 - biorxiv.org
The blood-brain barrier (BBB), formed by specialized brain microvascular endothelial cells
(BMECs), regulates brain function in health and disease. In vitro modeling of the human BBB …