Cortical inhibitory neurons exhibit remarkable diversity in their morphology, connectivity, and
synaptic properties. Here, we review the function of somatostatin-expressing (SOM) …

Epilepsy, one of the most common neurological disorders, often is not well controlled by
current pharmacological and surgical treatments. Sensory neuromodulation, including multi …

Single-cell analysis is revealing increasing diversity in gene expression profiles among
brain cells. Traditional promotor-based viral gene expression techniques, however, cannot …

Inhibitory microcircuits play an essential role in regulating cortical responses to sensory
stimuli. Interneurons that inhibit dendritic or somatic integration act as gatekeepers for neural …

The piriform cortex (PCx) receives direct input from the olfactory bulb (OB) and is the brain's
main station for odor recognition and memory. The transformation of the odor code from OB …

The basolateral amygdala (BLA) plays a vital role in associating sensory stimuli with salient
valence information. Excitatory principal neurons (PNs) undergo plastic changes to encode …

The mammalian sensory cortex is composed of multiple types of inhibitory and excitatory
neurons, which form sophisticated microcircuits for processing and transmitting sensory …

Alzheimer's and Parkinson's diseases are the most prevalent neurodegenerative disorders
in aging. Hyposmia has been described as an early symptom that can precede cognitive …

Social fear and avoidance of social partners and social situations represent the core
behavioral symptom of Social Anxiety Disorder (SAD), a prevalent psychiatric disorder …

Inhibitory modulation of glutamatergic information processing is a prerequisite for proper
network function. Among the many groups of interneurons (INs), somatostatin-expressing …