The pathogenesis of Ebola virus disease

L Baseler, DS Chertow, KM Johnson… - Annual Review of …, 2017 - annualreviews.org
For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

Ebola virus disease

D Malvy, AK McElroy, H de Clerck, S Günther… - The Lancet, 2019 - thelancet.com
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic
disease in man and great apes. Four species of ebolaviruses have been identified in west or …

A randomized, controlled trial of ZMapp for Ebola virus infection

Prevail II Writing Group - New England Journal of Medicine, 2016 - Mass Medical Soc
Background Data from studies in nonhuman primates suggest that the triple monoclonal
antibody cocktail ZMapp is a promising immune-based treatment for Ebola virus disease …

Diagnosis of Ebola virus disease: past, present, and future

MJ Broadhurst, TJG Brooks… - Clinical microbiology …, 2016 - Am Soc Microbiol
Laboratory diagnosis of Ebola virus disease plays a critical role in outbreak response efforts;
however, establishing safe and expeditious testing strategies for this high-biosafety-level …

Drug combinations as a first line of defense against coronaviruses and other emerging viruses

JM White, JT Schiffer, RA Bender Ignacio, S Xu… - MBio, 2021 - Am Soc Microbiol
The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-
equipped for future pandemics. While unprecedented strides have been made developing …

[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat

M Rojas, DM Monsalve, Y Pacheco… - Journal of …, 2020 - Elsevier
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

Ebola virus shedding and transmission: review of current evidence

P Vetter, WA Fischer, M Schibler… - The Journal of …, 2016 - academic.oup.com
Background. The magnitude of the 2013–2016 Ebola virus disease outbreak in West Africa
was unprecedented, with> 28 500 reported cases and> 11 000 deaths. Understanding the …

[HTML][HTML] Unique human immune signature of Ebola virus disease in Guinea

P Ruibal, L Oestereich, A Lüdtke, B Becker-Ziaja… - Nature, 2016 - nature.com
Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still
a fundamental lack of knowledge about the pathophysiology of EVD. In particular, very little …

[HTML][HTML] COVID-19 disease—temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and …

S Lanini, C Montaldo, E Nicastri, F Vairo, C Agrati… - PloS one, 2020 - journals.plos.org
Background Detailed temporal analyses of complete (full) blood count (CBC) parameters,
their evolution and relationship to patient age, gender, co-morbidities and management …

Antiviral activity of cationic amphiphilic drugs

C Salata, A Calistri, C Parolin… - Expert review of anti …, 2017 - Taylor & Francis
Introduction: Emerging and reemerging viral infections represent a major concern for human
and veterinary public health and there is an urgent need for the development of broad …