Fiber photometry is a key technique for characterizing brain-behavior relationships in vivo.
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …

We show that the sex of human experimenters affects mouse behaviors and responses
following administration of the rapid-acting antidepressant ketamine and its bioactive …

Understanding how dopamine (DA) encodes behavior depends on technologies that can
reliably monitor DA release in freely-behaving animals. Recently, red and green genetically …

Pleasurable touch is paramount during social behavior, including sexual encounters.
However, the identity and precise role of sensory neurons that transduce sexual touch …

With concurrent global epidemics of chronic pain and opioid use disorders, there is a critical
need to identify, target and manipulate specific cell populations expressing the mu-opioid …

Fiber photometry (FP) is an adaptable method for recording in vivo neural activity in freely
behaving animals. It has become a popular tool in neuroscience due to its ease of use, low …

The supraspinal descending pain modulatory system (DPMS) shapes pain perception via
monoaminergic modulation of sensory information in the spinal cord. However, the role and …

Chronic pain is a tremendous burden for afflicted individuals and society. Although opioids
effectively relieve pain, significant adverse outcomes limit their utility and efficacy. To …

The hippocampus is broadly impacted by neuromodulations. However, how neuropeptides
shape the function of the hippocampus and the related spatial learning and memory remains …

Traditional methods for site-specific drug delivery in the brain are slow, invasive, and difficult
to interface with recordings of neural activity. Here, we demonstrate the feasibility and …