Identification and treatment of latent tuberculosis infection (LTBI) can substantially reduce
the risk of developing active disease. However, there is no diagnostic gold standard for LTBI …

Mycobacterium tuberculosis uses sophisticated secretion systems, named 6 kDa early
secretory antigenic target (ESAT6) protein family secretion (ESX) systems (also known as …

Tuberculosis, an ancient disease of mankind, remains one of the major infectious causes of
human death. We examine newly discovered facets of tuberculosis pathogenesis and …

As a result of an error during film output, Table 1 was published with some symbols missing.
The correct version can be found at http://www. sanger. ac. uk and is reproduced again here …

Actinobacteria constitute one of the largest phyla among Bacteria and represent gram-
positive bacteria with a high G+ C content in their DNA. This bacterial group includes …

Mycobacterium species, including Mycobacterium tuberculosis and Mycobacterium leprae,
are among the most potent human bacterial pathogens. The discovery of cytosolic …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Current diagnostic tests for tuberculosis based on tuberculin have poor specificity, and both
BCG vaccination and exposure to non-tuberculosis mycobacteria produce a response …

Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and
man, with worldwide annual losses to agriculture of $3 billion. The human burden of …

A major challenge in tuberculosis control is the diagnosis and treatment of latent
tuberculosis infection. Until recently, there were no alternatives to the tuberculin skin test …