Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …

Maintenance of phosphate balance is essential for life, and mammals have developed a
sophisticated system to regulate phosphate homeostasis over the course of evolution …

Masafumi Fukagawa, 1 Keitaro Yokoyama, 1 Fumihiko Koiwa, 1 Masatomo Taniguchi, 1
Tetsuo Shoji, 1 Junichiro James Kazama, 1 Hirotaka Komaba, 1 Ryoichi Ando, 1 Takatoshi …

Parathyroidectomy (PTx) drastically improves biochemical parameters and clinical
symptoms related to severe secondary hyperparathyroidism (SHPT) but the effect of PTx on …

Background In patients on maintenance dialysis, cardiovascular mortality risk is remarkably
high, which can be partly explained by severe coronary artery calcification (CAC) …

Chronic kidney disease–mineral and bone disorder (CKD–MBD) is a systemic disorder that
affects multiple organs and systems and increases the risk of morbidity and mortality in …

Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney
disease (CKD). Multiple factors account for the increased incidence of cardiovascular …

It is well documented that chronic kidney disease patients have an extremely high risk of
developing cardiovascular (CV) disease (CVD) compared to the general population …

A series of problems including osteopathy, abnormal serum data, and vascular calcification
associated with chronic kidney disease (CKD) are now collectively called CKD-mineral bone …

Background Secondary hyperparathyroidism is a major complication of patients undergoing
hemodialysis (HD). Upacicalcet, a new injectable calcimimetic, acts on calcium-sensing …