Arsenic-mediated nephrotoxicity

ML Robles-Osorio, E Sabath-Silva, E Sabath - Renal failure, 2015 - Taylor & Francis
Chronic kidney disease (CKD) is an important global health problem that affects 8–15% of
the population according to epidemiological studies done in different countries. Essential to …

Cardiovascular adverse effects and mechanistic insights of arsenic exposure: a review

Y Wāng, L Ma, C Wang, T Gao, Y Han… - Environmental Chemistry …, 2024 - Springer
Human exposure to environmental arsenic induces cardiovascular diseases such as
arrhythmias, hypertension, and arteriosclerosis. Here, we review the toxicological and …

[HTML][HTML] Identifying early pathogenic events during vascular calcification in uremic rats

L Hortells, C Sosa, N Guillén, S Lucea, Á Millán… - Kidney international, 2017 - Elsevier
Vascular calcification in chronic kidney disease is a very complex process traditionally
explained in multifactorial terms. Here we sought to clarify relevance of the diverse agents …

Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory …

X Gong, VN Ivanov, MM Davidson, TK Hei - Archives of Toxicology, 2015 - Springer
Although kidney is a target organ of arsenic cytotoxicity, the underlying mechanisms of
arsenic-induced nephrotoxicity remain poorly understood. As tetramethylpyrazine (TMP) has …

Antioxidants protect against arsenic induced mitochondrial cardio-toxicity

C Pace, R Dagda, J Angermann - Toxics, 2017 - mdpi.com
Arsenic is a potent cardiovascular toxicant associated with numerous biomarkers of
cardiovascular diseases in exposed human populations. Arsenic is also a carcinogen, yet …

Exploring molecular profiles of calcification in aortic vascular smooth muscle cells and aortic valvular interstitial cells

JR Kessler, TS Bluemn, SA DeCero, P Dutta… - Journal of Molecular and …, 2023 - Elsevier
Cardiovascular calcification can occur in vascular and valvular structures and is commonly
associated with calcium deposition and tissue mineralization leading to stiffness and …

Arterial calcification: a new perspective?

R Nicoll, M Henein - International journal of cardiology, 2017 - Elsevier
Arterial calcification is commonly seen in atherosclerosis, chronic kidney disease (CKD) and
diabetes and has long been considered a natural progression of atherosclerosis. Yet it is a …

[HTML][HTML] Reactive oxygen species production in mitochondria of human gingival fibroblast induced by blue light irradiation

A Yoshida, F Yoshino, T Makita, Y Maehata… - … of Photochemistry and …, 2013 - Elsevier
In recent years, it has become well known that the production of reactive oxygen species
(ROS) induced by blue-light irradiation causes adverse effects of photo-aging, such as age …

Arsenic exposure through drinking water leads to senescence and alteration of telomere length in humans: A case‐control study in West Bengal, India

D Chatterjee, P Bhattacharjee, TJ Sau… - Molecular …, 2015 - Wiley Online Library
Arsenic (As) induces pre‐malignant and malignant dermatological lesions, non‐
dermatological health effects and cancers in humans. Senescence involves telomere length …

Transcriptome profile analysis reveals specific signatures of pollutants in Atlantic eels

L Baillon, F Pierron, R Coudret, E Normendeau… - Ecotoxicology, 2015 - Springer
Identifying specific effects of contaminants in a multi-stress field context remain a challenge
in ecotoxicology. In this context,“omics” technologies, by allowing the simultaneous …