Sample preparation and detection methods in point-of-care devices towards future at-home testing

G Adedokun, M Alipanah, ZH Fan - Lab on a Chip, 2024 - pubs.rsc.org
Timely and accurate diagnosis is critical for effective healthcare, yet nearly half the global
population lacks access to basic diagnostics. Point-of-care (POC) testing offers partial …

Cortisol: Biosensing and detection strategies

S Balasamy, R Atchudan, S Arya, BM Gunasekaran… - Clinica Chimica …, 2024 - Elsevier
Cortisol, a crucial steroid hormone synthesized by the adrenal glands, has diverse impacts
on multiple physiological processes, such as metabolism, immune function, and stress …

Multiplexed reverse-transcriptase quantitative polymerase chain reaction using plasmonic nanoparticles for point-of-care COVID-19 diagnosis

NR Blumenfeld, MAE Bolene, M Jaspan… - Nature …, 2022 - nature.com
Quantitative polymerase chain reaction (qPCR) offers the capabilities of real-time monitoring
of amplified products, fast detection, and quantitation of infectious units, but poses technical …

[PDF][PDF] Revolutionizing infectious disease management in low-resource settings: The impact of rapid diagnostic technologies and portable devices

AO Olatunji, JA Olaboye, CC Maha… - … Journal of Applied …, 2024 - researchgate.net
Olatunji, Olaboye, Maha, Kolawole, & Abdul, P. No. 1417-1432 Page 1418 services to
remote and underserved areas. These devices are designed to be user-friendly, requiring …

Rapid and accurate on-site immunodiagnostics of highly contagious severe acute respiratory syndrome coronavirus 2 using portable surface-enhanced Raman …

Y Joung, K Kim, S Lee, BS Chun, S Lee, J Hwang… - Acs …, 2022 - ACS Publications
In early 2022, the number of people infected with the highly contagious mutant severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), called Omicron, was increasing …

A glucose meter interface for point-of-care gene circuit-based diagnostics

E Amalfitano, M Karlikow, M Norouzi, K Jaenes… - Nature …, 2021 - nature.com
Recent advances in cell-free synthetic biology have given rise to gene circuit-based sensors
with the potential to provide decentralized and low-cost molecular diagnostics. However, it …

A sample-to-answer, quantitative real-time PCR system with low-cost, gravity-driven microfluidic cartridge for rapid detection of SARS-CoV-2, influenza A/B, and …

Y Zai, C Min, Z Wang, Y Ding, H Zhao, E Su, N He - Lab on a Chip, 2022 - pubs.rsc.org
The pandemic of coronavirus disease 2019 (COVID-19), due to the novel coronavirus
(SARS-CoV-2), has created an unprecedented threat to the global health system, especially …

Automated sample-to-answer centrifugal microfluidic system for rapid molecular diagnostics of SARS-CoV-2

L Malic, D Brassard, D Da Fonte, C Nassif, M Mounier… - Lab on a Chip, 2022 - pubs.rsc.org
Testing for SARS-CoV-2 is one of the most important assets in COVID-19 management and
mitigation. At the onset of the pandemic, SARS-CoV-2 testing was uniquely performed in …

Hollow microneedle microfluidic paper-based chip for biomolecules rapid sampling and detection in interstitial fluid

J Cheng, J Huang, Q Xiang, H Dong - Analytica Chimica Acta, 2023 - Elsevier
The interstitial fluid (ISF) contains rich bioinformation for disease diagnosis and healthcare
monitoring. However, the efficient sampling and detection of the biomolecules in ISF is still …

New technologies and reagents in lateral flow assay (LFA) designs for enhancing accuracy and sensitivity

MK Dey, M Iftesum, R Devireddy, MR Gartia - Analytical Methods, 2023 - pubs.rsc.org
Lateral flow assays (LFAs) are a popular method for quick and affordable diagnostic testing
because they are easy to use, portable, and user-friendly. However, LFA design has always …