Abstract Purpose of Review To provide updates on recent advances in the diagnosis and
management of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome …

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
diseases characterized by detachment of the epidermis and mucous membrane. SJS/TEN …

Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for
immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of …

Drug reaction with eosinophilia and systemic symptoms (DReSS), also known as drug-
induced hypersensitivity syndrome (DiHS), is a severe, systemic, T cell mediated drug …

The integration of genomic data into personalized treatment planning has revolutionized
oncology care. Despite this, patients with cancer remain vulnerable to high rates of adverse …

Drug-induced hypersensitivity syndrome (DiHS), also known as drug reaction with
eosinophilia and systemic symptoms (DRESS), is a severe cutaneous adverse reaction …

Returning incidental findings in African genomics research | Nature Genetics Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

The origins of pharmacogenetics date back to the 1950s, when it was established that inter-
individual differences in drug response are partially determined by genetic factors. Since …

The pathogenesis of SJS/TEN remains unclear and effective therapeutic agents have not yet
been established. As the involvement of innate immunity, such as monocytes and …

Drug hypersensitivity reactions are a serious concern in clinical practice because they can
be severe and result in lifelong sequelae. An accurate diagnosis and identification of the …