[HTML][HTML] Vitamin C and immune function

AC Carr, S Maggini - Nutrients, 2017 - mdpi.com
Vitamin C is an essential micronutrient for humans, with pleiotropic functions related to its
ability to donate electrons. It is a potent antioxidant and a cofactor for a family of biosynthetic …

Vitamin C in plants: from functions to biofortification

C Paciolla, S Fortunato, N Dipierro, A Paradiso… - Antioxidants, 2019 - mdpi.com
Vitamin C (l-ascorbic acid) is an excellent free radical scavenger, not only for its capability to
donate reducing equivalents but also for the relative stability of the derived …

Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

AC Carr, PC Rosengrave, S Bayer, S Chambers… - Critical care, 2017 - Springer
Background Vitamin C is an essential water-soluble nutrient which cannot be synthesised or
stored by humans. It is a potent antioxidant with anti-inflammatory and immune-supportive …

Pro‐and antioxidant effects of vitamin C in cancer in correspondence to its dietary and pharmacological concentrations

E Pawlowska, J Szczepanska… - Oxidative Medicine and …, 2019 - Wiley Online Library
Vitamin C is an antioxidant that may scavenge reactive oxygen species preventing DNA
damage and other effects important in cancer transformation. Dietary vitamin C from natural …

The epigenetic role of vitamin C in health and disease

V Camarena, G Wang - Cellular and Molecular Life Sciences, 2016 - Springer
Recent advances have uncovered a previously unknown function of vitamin C in epigenetic
regulation. Vitamin C exists predominantly as an ascorbate anion under physiological pH …

Potential mechanisms of action for vitamin C in cancer: reviewing the evidence

MCM Vissers, AB Das - Frontiers in physiology, 2018 - frontiersin.org
Whether vitamin C (ascorbate) has a role to play as an anti-cancer agent has been debated
for decades. Ascorbate has been used by cancer patients in an unregulated environment …

Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging

MA Sowers, JR McCombs, Y Wang, JT Paletta… - Nature …, 2014 - nature.com
Stimuli-responsive multimodality imaging agents have broad potential in medical
diagnostics. Herein, we report the development of a new class of branched-bottlebrush …

[HTML][HTML] NADP modulates RNA m6A methylation and adipogenesis via enhancing FTO activity

L Wang, C Song, N Wang, S Li, Q Liu, Z Sun… - Nature chemical …, 2020 - nature.com
Metabolism is often regulated by the transcription and translation of RNA. In turn, it is likely
that some metabolites regulate enzymes controlling reversible RNA modification, such as N …

Enhancing ascorbate in fruits and tubers through over‐expression of the l‐galactose pathway gene GDP‐l‐galactose phosphorylase

S Bulley, M Wright, C Rommens, H Yan… - Plant biotechnology …, 2012 - Wiley Online Library
Ascorbate, or vitamin C, is obtained by humans mostly from plant sources. Various
approaches have been made to increase ascorbate in plants by transgenic means. Most of …

Vitamin C promotes wound healing through novel pleiotropic mechanisms

BM Mohammed, BJ Fisher… - International wound …, 2016 - Wiley Online Library
Vitamin C (VitC) or ascorbic acid (AscA), a cofactor for collagen synthesis and a primary
antioxidant, is rapidly consumed post‐wounding. Parenteral VitC administration suppresses …