Immune lymphocyte infiltrate and its prognostic value in triple-negative breast cancer

CA Huertas-Caro, MA Ramirez… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) occurs more frequently in young (< 50 years) non-
Hispanic black and Hispanic/Latina women. It is considered the most aggressive subtype of …

Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience

NC Van der Merwe, HME Combrink, KS Ntaita… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is a multifaceted disease that currently represents a leading cause of death in
women worldwide. Over the past two decades (1998–2020), the National Health Laboratory …

Prevalence of specific and recurrent/founder pathogenic variants in BRCA genes in breast and ovarian cancer in North Africa

O ElBiad, A Laraqui, F El Boukhrissi, C Mounjid… - BMC cancer, 2022 - Springer
Background Elucidation of specific and recurrent/founder pathogenic variants (PVs) in
BRCA (BRCA1 and BRCA2) genes can make the genetic testing, for breast cancer (BC) …

Increased prevalence of the founder BRCA1 c.5309G>T and recurrent BRCA2 c.1310_1313delAAGA mutations in breast cancer families from Northerstern region of …

R Melki, M Melloul, S Aissaoui, T El Harroudi… - BMC cancer, 2023 - Springer
Background Inherited mutations in the breast cancer susceptibility genes BRCA1 and
BRCA2 (BRCA1/2) confer high risks of breast and ovarian cancer. Because the contribution …

[HTML][HTML] Identification of a novel pathogenic variant in PALB2 and BARD1 genes by a multigene sequencing panel in triple negative breast cancer in Morocco

A Laraqui, M Cavaillé, N Uhrhammer, O ElBiad… - Journal of …, 2021 - ncbi.nlm.nih.gov
Pathogenic variants (PVs) in BRCA genes have been mainly associated with an increasing
risk of triple negative breast cancer (TNBC). The contribution of PVs in non-BRCA genes to …

Triple-negative breast cancer (TNBC) occurs more frequently in young (< 50 years) non-Hispanic black and Hispanic/Latina women. It is considered the most …

TP Martínez, YQ Zhang, A Magliocco… - Reviews in Breast …, 2023 - books.google.com
Breast cancer (BC) is a heterogeneous disease in its phenotypic and genomic features (1).
Four intrinsic subtypes, luminal A, luminal B, HER2-enriched, and triple negative, have been …

[PDF][PDF] Abdelilah Laraqui1, 2✉, Mathias Cavaillé3, 4, Nancy Uhrhammer3, 4, Oubaida ElBiad1, 5, Yannick Bidet3, 4, Hicham El Rhaffouli2, Hicham El Anaz1, Driss …

M Ichou, K Ennibi, Y Sekhsokh, YJ Bignon - Journal of Genomics, 2021 - researchgate.net
Pathogenic variants (PVs) in BRCA genes have been mainly associated with an increasing
risk of triple negative breast cancer (TNBC). The contribution of PVs in non-BRCA genes to …

[PDF][PDF] Profil du spectre mutationnel des gènes BRCA dans la population marocaine: Identification des mutations fondatrices et récurrentes

B Lahbiba - 2021 - toubkal.imist.ma
Résumé Le cancer du sein est le cancer féminin le plus fréquemment diagnostique au
Maroc. Environ 5 à 10% sont dus à une prédisposition héréditaire et les mutations des …