Hypertension and endothelial dysfunction: therapeutic approach

L Ghiadoni, S Taddei, A Virdis - Current vascular …, 2012 - ingentaconnect.com
A large body of evidence indicates that patients with essential hypertension are
characterized by endothelial dysfunction mediated by an impaired NO availability secondary …

Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials

Y Shahin, JA Khan, N Samuel, I Chetter - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: Several studies have assessed the effect of angiotensin converting enzyme
inhibitors (ACEIs) on endothelial dysfunction as measured by brachial flow-mediated …

The endothelium and COVID-19: an increasingly clear link brief title: endotheliopathy in COVID-19

I Six, N Guillaume, V Jacob, R Mentaverri… - International Journal of …, 2022 - mdpi.com
The endothelium has a fundamental role in the cardiovascular complications of coronavirus
disease 2019 (COVID-19). Infection with severe acute respiratory syndrome coronavirus 2 …

Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system

G Cirino, V Vellecco, M Bucci - British journal of pharmacology, 2017 - Wiley Online Library
There are several reviews on NO and hydrogen sulfide (H2S) and their role in vascular
diseases in the current relevant literature. The aim of this review is to discuss, within the …

Effect of the long-term intake of an egg white hydrolysate on the oxidative status and blood lipid profile of spontaneously hypertensive rats

MA Manso, M Miguel, J Even, R Hernández… - Food chemistry, 2008 - Elsevier
This paper examines the effects of the long-term consumption of egg white hydrolysed with
pepsin (hEW) on the antioxidant status and lipid profile of spontaneously hypertensive rats …

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition

M Bucci, V Vellecco, A Cantalupo… - Cardiovascular …, 2014 - academic.oup.com
Aims Therapeutic use of sulfhydrylated inhibitor S-zofenopril has raised different hypotheses
regarding the role played by its thiol group in the beneficial clinical effects exerted compared …

Impairment of anti-aggregatory responses to nitric oxide and prostacyclin: mechanisms and clinical implications in cardiovascular disease

YY Chirkov, TH Nguyen, JD Horowitz - International Journal of Molecular …, 2022 - mdpi.com
The propensity towards platelet-rich thrombus formation increases substantially during
normal ageing, and this trend is mediated by decreases in platelet responsiveness to the …

Influence of beta-blockers on endothelial function: a meta-analysis of randomized controlled trials

M Peller, K Ozierański, P Balsam… - Cardiology …, 2015 - journals.viamedica.pl
Background: Endothelial dysfunction (ED) frequently precedes cardiovascular diseases
(CVD) and is a well-established risk factor of major adverse cardiac events. Beta-blockers …

Changes of the coronary arteries and cardiac microvasculature with aging: Implications for translational research and clinical practice

F Piccirillo, M Carpenito, G Verolino, C Chello… - Mechanisms of ageing …, 2019 - Elsevier
Aging results in functional and structural changes in the cardiovascular system, translating
into a progressive increase of mechanical vessel stiffness, due to a combination of changes …

Effects of zofenopril on arterial stiffness in hypertension patients

B Palić, I Brizić, EK Sher, I Cvetković… - Molecular …, 2023 - Springer
Angiotensin-converting enzyme inhibitors (ACEIs) reduce arterial stiffness beyond their
antihypertensive effect. Studies showed that sulfhydryl ACEIs have the antioxidative …