Skin aging is one of the most evident signs of human aging. Modification of the skin during
the life span is characterized by fine lines and wrinkling, loss of elasticity and volume, laxity …

The skin, being the barrier organ of the body, is constitutively exposed to various stimuli
impacting its morphology and function. Senescent cells have been found to accumulate with …

Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …

Cellular senescence and aging result in a reduced ability to manage persistent types of
inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is …

The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …

During the past decade, melanins and melanogenesis have attracted growing interest for a
broad range of biomedical and technological applications. The burst of polydopamine …

Aging is an inherently complex process that is manifested within an organism at genetic,
molecular, cellular, organ, and system levels. Although the fundamental mechanisms are …

Hair greying (canities) is one of the earliest, most visible ageing‐associated phenomena,
whose modulation by genetic, psychoemotional, oxidative, senescence‐associated …

Everyone knows and seems to agree that melanocytes are there to generate melanin–an
intriguing, but underestimated multipurpose molecule that is capable of doing far more than …

Oxidative stress is an unbalanced condition in which the tissues of the body are not
sufficiently able to counteract either exogenous or endogenous sources of reactive oxygen …