Lipid droplet functions beyond energy storage
Lipid droplets are cytoplasmic organelles that store neutral lipids and are critically important
for energy metabolism. Their function in energy storage is firmly established and …
for energy metabolism. Their function in energy storage is firmly established and …
Lipid droplets in health and disease
Lipids are essential building blocks synthesized by complex molecular pathways and
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
The emergence and global spread of SARS-CoV-2 has resulted in the urgent need for an in-
depth understanding of molecular functions of viral proteins and their interactions with the …
depth understanding of molecular functions of viral proteins and their interactions with the …
The assembly of lipid droplets and their roles in challenged cells
WM Henne, ML Reese, JM Goodman - The EMBO journal, 2018 - embopress.org
Cytoplasmic lipid droplets are important organelles in nearly every eukaryotic and some
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …
Lipid droplets finally get a little RESPECT
RV Farese, TC Walther - Cell, 2009 - cell.com
Long underappreciated as important cellular organelles, lipid droplets are finally being
recognized as dynamic structures with a complex and interesting biology. In light of this …
recognized as dynamic structures with a complex and interesting biology. In light of this …
Lipophagy: connecting autophagy and lipid metabolism
Lipid droplets (LDs), initially considered “inert” lipid deposits, have gained during the last
decade the classification of cytosolic organelles due to their defined composition and the …
decade the classification of cytosolic organelles due to their defined composition and the …
Not just fat: the structure and function of the lipid droplet
T Fujimoto, RG Parton - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
The known unknowns of antigen processing and presentation
The principal components of both MHC class I and class II antigen processing and
presentation pathways are well known. In dendritic cells, these pathways are tightly …
presentation pathways are well known. In dendritic cells, these pathways are tightly …
The lipid droplet—a well-connected organelle
Q Gao, JM Goodman - Frontiers in cell and developmental biology, 2015 - frontiersin.org
Our knowledge of inter-organellar communication has grown exponentially in recent years.
This review focuses on the interactions that cytoplasmic lipid droplets have with other …
This review focuses on the interactions that cytoplasmic lipid droplets have with other …
The mammalian endoplasmic reticulum-associated degradation system
JA Olzmann, RR Kopito… - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
The endoplasmic reticulum (ER) is the site of synthesis for nearly one-third of the eukaryotic
proteome and is accordingly endowed with specialized machinery to ensure that proteins …
proteome and is accordingly endowed with specialized machinery to ensure that proteins …