Cancer is one of the most common causes of death globally. Despite extensive research
and considerable advances in cancer therapy, the fundamentals of the disease remain …

In recent years, advances in the understanding of low-grade glioma (LGG) biology have
driven new paradigms in molecular markers, diagnostic imaging, operative techniques and …

ABSTRACT TRAF6 (TNF receptor associated factor 6) plays a pivotal role in NFKB activation
and macroautphagy/autophagy activation induced by TLR4 (toll like receptor 4) signaling …

Thiol proteins may potentially act as redox signaling adaptor proteins, adjusting reactive
oxygen species intermediates to specific signals and redox signals to cell homeostasis. In …

Gliomas are a heterogenous group of malignant primary brain tumors that arise from glia
cells or their progenitors and rely on accurate diagnosis for prognosis and treatment …

Gliomas in the form of astrocytomas, anaplastic astrocytomas and glioblastomas are the
most common brain tumors in humans. Early detection of these cancers is crucial for …

Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to
radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are …

Purpose To investigate the biochemical origin of the amide photon transfer (APT)-weighted
hyperintensity in brain tumors. Procedures Seven 9 L gliosarcoma-bearing rats were imaged …

Abstract Peroxiredoxin 6 (PRDX6), the only mammalian 1-Cys member of the
peroxiredoxins (PRDXs) family, has multiple functions of glutathione peroxidase (Gpx) …

In the past, many chromosomal and genetic alterations have been examined as possible
causes of cancer. However, some tumors do not display a clear molecular and/or genetic …