Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its
physiological role is much larger and encompasses very different processes ranging from …

Background and aims Vitamin C has been used as an anti-oxidant in various diseases
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Background Vitamin C is an essential water-soluble nutrient that functions as a key
antioxidant and has been proven to be effective for boosting immunity. In this study, we …

Importance Sepsis is a common syndrome with substantial morbidity and mortality. A
combination of vitamin C, thiamine, and corticosteroids has been proposed as a potential …

Background Our recent meta-analysis indicated that vitamin C may shorten the length of ICU
stay and the duration of mechanical ventilation. Here we analyze modification of the vitamin …

Purpose To evaluate the effects of early combination therapy with intravenous vitamin C and
thiamine on recovery from organ failure in patients with septic shock. Methods The ascorbic …

Background The coronavirus disease 2019 (COVID-19) is a pandemic caused by
coronavirus with mild to severe respiratory symptoms. This paper aimed to investigate the …

Background Supplementation of vitamin C in septic patients remains controversial despite
eight large clinical trials published only in 2020. We aimed to evaluate the evidence on …

Head trauma is the most common cause of disability in young adults. Known as a silent
epidemic, it can cause a mosaic of symptoms, whether neurological (sensory–motor …