Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Essential oils and antifungal activity

F Nazzaro, F Fratianni, R Coppola, V De Feo - Pharmaceuticals, 2017 - mdpi.com
Since ancient times, folk medicine and agro-food science have benefitted from the use of
plant derivatives, such as essential oils, to combat different diseases, as well as to preserve …

Regulation and role of fungal secondary metabolites

J Macheleidt, DJ Mattern, J Fischer… - Annual review of …, 2016 - annualreviews.org
Fungi have the capability to produce a tremendous number of so-called secondary
metabolites, which possess a multitude of functions, eg, communication signals during …

Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

KJ Kwon-Chung, JA Sugui - PLoS pathogens, 2013 - journals.plos.org
Aspergillus fumigatus, the major cause of life threatening invasive aspergillosis (IA), is a
ubiquitous saprophytic fungus to which humans are exposed daily in most parts of the world …

The birth, evolution and death of metabolic gene clusters in fungi

A Rokas, JH Wisecaver, AL Lind - Nature Reviews Microbiology, 2018 - nature.com
Fungi contain a remarkable diversity of both primary and secondary metabolic pathways
involved in ecologically specialized or accessory functions. Genes in these pathways are …

A global coexpression network approach for connecting genes to specialized metabolic pathways in plants

JH Wisecaver, AT Borowsky, V Tzin, G Jander… - The Plant …, 2017 - academic.oup.com
Plants produce diverse specialized metabolites (SMs), but the genes responsible for their
production and regulation remain largely unknown, hindering efforts to tap plant …

Fungal biofilms

S Fanning, AP Mitchell - PLoS pathogens, 2012 - journals.plos.org
Biofilms are a principal form of microbial growth and are critical to development of clinical
infection. They are responsible for a broad spectrum of microbial infections in the human …

Fungal biofilms, drug resistance, and recurrent infection

JV Desai, AP Mitchell… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
A biofilm is a surface-associated microbial community. Diverse fungi are capable of biofilm
growth. The significance of this growth form for infection biology is that biofilm formation on …

The interface between fungal biofilms and innate immunity

JF Kernien, BD Snarr, DC Sheppard… - Frontiers in …, 2018 - frontiersin.org
Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix.
These biofilms are commonly found during infection caused by a variety of fungal …

Aspergillus fumigatus biofilms: Toward understanding how growth as a multicellular network increases antifungal resistance and disease progression

KA Morelli, JD Kerkaert, RA Cramer - PLoS Pathogens, 2021 - journals.plos.org
Aspergillus fumigatus is a saprophytic, filamentous fungus found in soils and compost and
the causative agent of several pulmonary diseases in humans, birds, and other mammals. A …