An overview of the structure and function of the flagellar hook FlgE protein

Y You, F Ye, W Mao, H Yang, J Lai, S Deng - World Journal of …, 2023 - Springer
The flagellum is an important organelle for the survival of bacteria and consists of a basal
body, hook, and filament. The FlgE protein is the subunit of the hook that connects the basal …

An integrative reverse vaccinology, immunoinformatic, docking and simulation approaches towards designing of multi-epitopes based vaccine against monkeypox …

A Ullah, FA Shahid, MU Haq… - Journal of …, 2023 - Taylor & Francis
Monkeypox is a viral zoonotic disease that is caused by the monkeypox virus (MPXV) and is
mainly transmitted to human through close contact with an infected person, animal, or …

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

Designing of a Recombinant Multi-Epitopes Based Vaccine against Enterococcus mundtii Using Bioinformatics and Immunoinformatics Approaches

M Alharbi, A Alshammari, AF Alasmari… - International journal of …, 2022 - mdpi.com
Enterococcus species are an emerging group of bacterial pathogens that have a significant
role in hospital-associated infections and are associated with higher mortality and morbidity …

Computer-Aided Multi-Epitope Vaccine Design against Enterobacter xiangfangensis

A Alshammari, M Alharbi, A Alghamdi… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance is a global public health threat and is associated with high mortality due
to antibiotics' inability to treat bacterial infections. Enterobacter xiangfangensis is an …

Vaccinomics to design a multi-epitope-based vaccine against monkeypox virus using surface-associated proteins

S Khan, M Irfan, AR Hameed, A Ullah… - Journal of …, 2023 - Taylor & Francis
In 2022, the ongoing multi-country outbreak of monkeypox virus—now occurring outside
Africa, too is a global health concern. Monkeypox is a zoonotic virus, which causes disease …

Development of a Novel Vaccine Candidates against Cardiobacterium valvarum through Reverse Vaccinology and Computational Approaches

FF Albaqami, A Altharawi, HN Althurwi… - BioMed Research …, 2023 - Wiley Online Library
Antibiotic resistance is a major public health concern that has resulted in high healthcare
costs, increased mortality, and the emergence of novel bacterial diseases. Cardiobacterium …

Proteome-Wide Screening of Potential Vaccine Targets against Brucella melitensis

M Malik, S Khan, A Ullah, M Hassan, M Haq, S Ahmad… - Vaccines, 2023 - mdpi.com
The ongoing antibiotic-resistance crisis is becoming a global problem affecting public
health. Urgent efforts are required to design novel therapeutics against pathogenic bacterial …

Integrated computer-aided drug design and biophysical simulation approaches to determine natural anti-bacterial compounds for Acinetobacter baumannii

RAH Almihyawi, ZT Naman, HMH Al-Hasani… - Scientific reports, 2022 - nature.com
Acinetobacter baumannii is a nosocomial bacterial pathogen and is responsible for a wide
range of diseases including pneumonia, necrotizing fasciitis, meningitis, and sepsis. The …

Evidence of the efficiency of reverse vaccinology against bovine parasites: a systematic review

BCF Nogueira, NTBS Honório, PE de Almeida Souza… - Acta Tropica, 2024 - Elsevier
Reverse vaccinology is a novel vaccine development technology that uses genome and
proteome analyses through bioinformatics to select antigenic epitopes capable of eliciting …