Palmar erythema

R Serrao, M Zirwas, JC English - American journal of clinical dermatology, 2007 - Springer
Palmar erythema (PE), an often overlooked physical finding, is due to several physiologic or
systemic pathologic states. PE can exist as a primary physiologic finding or as a secondary …

[HTML][HTML] Amiodarone-induced cirrhosis of liver: what predicts mortality?

N Hussain, A Bhattacharyya… - International Scholarly …, 2013 - hindawi.com
Introduction. Amiodarone has been used for more than 5 decades for the treatment of
various tachyarrhythmias and previously for the treatment of refractory angina. There are …

Safety of amiodarone in the prevention of postoperative atrial fibrillation: a meta-analysis

AA Patel, CM White, EL Gillespie… - American Journal of …, 2006 - academic.oup.com
Purpose. A meta-analysis was conducted to assess the safety of amiodarone in the
prevention of postoperative atrial fibrillation. Methods. A search of the medical literature was …

Amiodarone alters cholesterol biosynthesis through tissue-dependent inhibition of emopamil binding protein and dehydrocholesterol reductase 24

LB Allen, TC Genaro-Mattos, A Anderson… - ACS chemical …, 2020 - ACS Publications
Amiodarone is prescribed for the treatment and prevention of irregular heartbeats. Although
effective in clinical practice, the long-term use of amiodarone has many unwanted side …

Free radical scavenging and hepatoprotective constituents from the leaves of Juglans sinensis

RB An, HC Kim, YH Tian, YC Kim - Archives of pharmacal research, 2005 - Springer
In the course of searching for hepatoprotective agents from natural products, six compounds
were isolated from the MeOH extract of the leaves of Juglans sinensis, as guided by their …

[HTML][HTML] Mitochondrial dysfunction and delayed hepatotoxicity: another lesson from troglitazone

NL Julie, IM Julie, AI Kende, GL Wilson - Diabetologia, 2008 - Springer
Aims/hypothesis Troglitazone was approved for treatment of type 2 diabetes mellitus, but by
2000 it had been removed from all world markets due to severe drug-induced liver injury …

Hepatotoxicity and hepatic metabolism of available drugs: current problems and possible solutions in preclinical stages

S Giri, K Nieber, A Bader - Expert Opinion on Drug Metabolism & …, 2010 - Taylor & Francis
Importance of the filed: According to a 2006 survey report of pharmaceutical companies,
hepatotoxicity was ranked first in terms of adverse events and it remains the most common …

Hepatic cirrhosis caused by low-dose oral amiodarone therapy

SR Puli, MA Fraley, V Puli, AB Kuperman… - The American journal of …, 2005 - Elsevier
A 63-year-old man presented with ascites after therapy with amiodarone, 200 mg orally once
per day for 22.5 months. A liver biopsy showed grade 3 chronic hepatitis and micronodular …

Familial Mediterranean fever and cryptogenic cirrhosis

N Tweezer-Zaks, A Doron-Libner, P Weiss… - Medicine, 2007 - journals.lww.com
Familial Mediterranean fever (FMF) is a febrile disease characterized by acute,
spontaneously resolving episodes of fever and pain caused by serosal inflammation and …

Toxins mechanism in instigating hepatotoxicity

S Nithiyanandam, S Evan Prince - Toxin Reviews, 2021 - Taylor & Francis
Myriad of therapeutic drugs used in clinical practice have led to hepatotoxicity reporting
more than 1,100 pharmaceutical and chemical products with liver injury. Drug-induced liver …