[HTML][HTML] Metabolically healthy obesity: facts and fantasies

GI Smith, B Mittendorfer, S Klein - The Journal of clinical …, 2019 - Am Soc Clin Investig
Although obesity is typically associated with metabolic dysfunction and cardiometabolic
diseases, some people with obesity are protected from many of the adverse metabolic …

[HTML][HTML] Cardiovascular risk and obesity

C Cercato, FA Fonseca - Diabetology & metabolic syndrome, 2019 - Springer
Background This is an overview of the mechanisms of obesity and its relation to
cardiovascular risks, describing the available treatment options to manage this condition …

The definition and prevalence of obesity and metabolic syndrome

A Engin - Obesity and lipotoxicity, 2017 - Springer
Increase in prevalence of obesity has become a worldwide major health problem in adults,
as well as among children and adolescents. Furthermore, total adiposity and truncal …

Obesity and cardiovascular disease: revisiting an old relationship

C Koliaki, S Liatis, A Kokkinos - Metabolism, 2019 - Elsevier
A wealth of clinical and epidemiological evidence has linked obesity to a broad spectrum of
cardiovascular diseases (CVD) including coronary heart disease, heart failure …

BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million …

D Aune, A Sen, M Prasad, T Norat, I Janszky… - bmj, 2016 - bmj.com
Objective To conduct a systematic review and meta-analysis of cohort studies of body mass
index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the …

[HTML][HTML] Relevance of body composition in phenotyping the obesities

L Salmón-Gómez, V Catalán, G Frühbeck… - Reviews in Endocrine …, 2023 - Springer
Obesity is the most extended metabolic alteration worldwide increasing the risk for the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

Obesity phenotypes and their paradoxical association with cardiovascular diseases

A Vecchié, F Dallegri, F Carbone… - European journal of …, 2018 - Elsevier
The pro-inflammatory state of the visceral adipose tissue (VAT) is supposed to accelerate
cardiovascular (CV) and metabolic diseases in obese subjects. Some studies have recently …

Are metabolically healthy overweight and obesity benign conditions? A systematic review and meta-analysis

CK Kramer, B Zinman, R Retnakaran - Annals of internal medicine, 2013 - acpjournals.org
Background: Recent interest has focused on a unique subgroup of overweight and obese
individuals who have normal metabolic features despite increased adiposity. Normal-weight …

Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups

A Lonardo, S Bellentani, CK Argo, S Ballestri… - Digestive and Liver …, 2015 - Elsevier
An improved understanding of non-alcoholic fatty liver disease epidemiology would lead to
identification of individuals at high risk of developing chronic liver disease and extra-hepatic …

Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications

N Stefan, HU Häring, FB Hu… - The lancet Diabetes & …, 2013 - thelancet.com
Obesity has become a worldwide epidemic that poses substantial health problems for both
individuals and society. However, a proportion of obese individuals might not be at an …