Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central
and peripheral nervous systems and with diverse roles in multiple physiological processes …

Substantial evidence shows that neoplastic and nonneoplastic tissue growth is dependent
on angiogenesis. Neovascularization and adipogenesis are temporally and spatially …

The relationship between stress and obesity remains elusive. In response to stress, some
people lose weight, whereas others gain. Here we report that stress exaggerates diet …

The study of gene expression profiling of cells and tissue has become a major tool for
discovery in medicine. Microarray experiments allow description of genome-wide …

Pericellular proteases play an important role in angiogenesis and vasculogenesis. They
comprise (membrane-type) matrix metalloproteinases [(MT-) MMPs], serine proteases …

The volume of extracellular fluid (ECF) is maintained within narrow limits in normal human
subjects, despite day-to-day variations in dietary intake of salt and water over a wide range …

DP (dipeptidyl peptidase) IV is the archetypal member of its six-member gene family. Four
members of this family, DPIV, FAP (fibroblast activation protein), DP8 and DP9, have a rare …

Dipeptydil-peptidase-4 (DPP-4) inhibitors are available as oral anti-hyperglycemic drugs for
the treatment of type 2 diabetes. Their metabolic effect is mediated through sparing incretin …

Aim Ischemic damage to the brain is linked to an increased rate of morbidity and mortality
worldwide. In certain parts of the world, it remains a leading cause of mortality and the …