Cells contain molecules, which become fluorescent when excited by UV/Vis radiation of
suitable wavelength. This fluorescence emission, arising from endogenous fluorophores, is …

▪ Abstract The interaction of light within tissue has been used to recognize disease since the
mid-1800s. The recent developments of small light sources, detectors, and fiber optic probes …

Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

Fast and non-invasive, diagnostic techniques based on fluorescence spectroscopy have the
potential to link the biochemical and morphologic properties of tissues to individual patient …

Optical spectroscopy has been extensively studied as a potential in vivo diagnostic tool that
can provide information about both the chemical and morphologic structure of tissue in near …

Predictions from Mie theory regarding the wavelength dependence of scattering in tissue
from the near UV to the near IR are discussed and compared with experiments on tissue …

Biochemical estimation of NADH concentration is a useful method for monitoring cellular
metabolism, because the NADH/NAD+ reduction-oxidation pair is crucial for electron …

Normal mitochondrial function is a critical factor in maintaining cellular homeostasis in
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …

During the development of neoplasia, epithelial tissues undergo biochemical and structural
changes that can manifest in tissue fluorescence. There have been several reports on …

Optical spectroscopy methods are fast emerging as potential alternatives for early diagnosis
of cancer. A Raman spectroscopy method for discrimination of normal and malignant oral …