It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …

In the past 2 decades, it has become evident that individuals born with congenital heart
disease (CHD) are at risk of developing life-long neurological deficits. Multifactorial risk …

Congenital heart disease (CHD) is the leading cause of mortality from birth defects. Here,
exome sequencing of a single cohort of 2,871 CHD probands, including 2,645 parent …

BACKGROUND: Neurodevelopmental disability is the most common complication for
survivors of surgery for congenital heart disease (CHD). METHODS: We analyzed individual …

Congenital heart disease (CHD) patients have an increased prevalence of extracardiac
congenital anomalies (CAs) and risk of neurodevelopmental disabilities (NDDs). Exome …

Aim (1) To systematically review the literature on developmental outcomes from infancy to
adolescence of children with complex congenital heart disease (CHD) who underwent early …

Neurodevelopmental impairment is a common and important long-term morbidity among
infants with congenital heart disease (CHD). More than half of those with complex CHD will …

BACKGROUND: Low socioeconomic status (SES) has emerged as an important risk factor
for higher short-term mortality and neurodevelopmental outcomes in children with …

Background People with a Fontan circulation experience a range of physical, psychosocial
and neurodevelopmental challenges alongside, or caused by, their cardiac condition, with …

Background Children with single ventricle heart disease require frequent interventions and
follow‐up. Low socioeconomic status (SES) may limit access to high‐quality care and place …