Plasmodium vivax is the most geographically widespread of the malaria parasites causing
human disease, yet it is comparatively understudied compared with Plasmodium falciparum …

Behçet's syndrome (BS) is a systemic vasculitis with several clinical manifestations.
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …

Human African trypanosomiasis due to Trypanosoma brucei rhodesiense is invariably fatal if
untreated with up to 12.3 million people at a risk of developing the disease in Sub-Saharan …

Globally, malaria and human immunodeficiency virus (HIV) are both independently
associated with a massive burden of disease and death. While their co-infection has been …

Background Plasmodium vivax is the causative agent of human malaria of large geographic
distribution, with 35 million cases annually. In Brazil, it is the most prevalent species, being …

Snakebites are a serious public health problem and, in the Amazon, the Bothrops atrox
snake is the most frequent cause of envenomation. B. atrox venom (BaV) causes …

Background The clinical outcome of malaria depends on the delicate balance between pro-
inflammatory and immunomodulatory cytokine responses triggered during infection. Despite …

Background. With 214 million cases and 438,000 deaths in 2015, malaria remains one of
the deadliest infectious diseases in tropical countries. Several species of the protozoan …

Malaria is a major infectious disease in several countries and is caused by protozoa of the
genus Plasmodium. In vivax malaria patients, inflammatory processes occur, as well as …

Snakebites are considered a major public health problem worldwide. In the Amazon region
of Brazil, the snake Bothrops atrox (B. atrox) is responsible for 90% of the bites. These bites …