An Allosteric Inhibitory Potential of Triterpenes from Combretum racemosum on the Structural and Functional Dynamics of Plasmodium falciparum Lactate …
Multidrug resistance is a significant drawback in malaria treatment, and mutations in the
active sites of the many critical antimalarial drug targets have remained challenging …
active sites of the many critical antimalarial drug targets have remained challenging …
Antimalarial potential of compounds isolated from Mammea siamensis T. Anders. flowers: in vitro and molecular docking studies
Background: The emergence of antimalarial drug resistance encourages the search for new
antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a …
antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a …
In Silico Studies of Four Compounds of Cecropia obtusifolia against Malaria Parasite
CA Lobato-Tapia, Y Moreno-Hernández… - Molecules, 2023 - mdpi.com
Malaria is a disease that affects many people in the world. In Mexico, malaria remains an
active disease in certain regions, particularly in the states of Chiapas and Chihuahua. While …
active disease in certain regions, particularly in the states of Chiapas and Chihuahua. While …
[PDF][PDF] Molecular docking study of the interactions between Plasmodium falciparum lactate dehydrogenase and 4-aminoquinoline hybrids
NH Zakaria, NI Hassan, LK Wai - Sains Malaysiana, 2020 - ukm.my
Malaria is a potentially deadly disease with many anti-malarial drugs have been rendered
ineffective due to Plasmodium falciparum resistance concern. Plasmodium falciparum …
ineffective due to Plasmodium falciparum resistance concern. Plasmodium falciparum …
[PDF][PDF] High-Throughput Virtual Screening with Molecular Docking, Pharmacophore Modelling and ADME Prediction to Discover Potential Inhibitors of Plasmodium …
The increased prevalence of malaria requires continuous efforts towards the discovery of
natural antimalarial agents targeting important biochemical pathways of the parasite. The …
natural antimalarial agents targeting important biochemical pathways of the parasite. The …
[PDF][PDF] Computational simulations of phytoconstituents derived from Phyllanthus amarus against Plasmodium falciparum molecular targets
A FID, S Ibrahim - Drug Discovery, 2023 - researchgate.net
There has been an increase in the resistance of plasmodium parasites to already available
malaria prevention drugs. Hence, the need for novel malaria-preventive medications. This …
malaria prevention drugs. Hence, the need for novel malaria-preventive medications. This …
Uncovering the inhibitory potentials of Phyllanthus nivosus leaf and its bioactive compounds against Plasmodium lactate dehydrogenase for malaria therapy
TO Johnson, AE Adegboyega, GI Johnson… - Journal of …, 2023 - Taylor & Francis
Malaria control efforts have been hampered due to the emergence of resistant malaria
parasite strains and the coinciding events of Covid-19. The quest for more effective and safe …
parasite strains and the coinciding events of Covid-19. The quest for more effective and safe …
[PDF][PDF] Synthesis and Molecular Docking Studies of Pyrano [2, 3-c] Pyrazole-3-Carboxylates as Potential Inhibitors of Plasmodium Falciparum
MA Shamsuddin, NH Zakaria, MF Mohammat… - Malays. J …, 2020 - researchgate.net
Plasmodium falciparum is the most virulent species of human malaria. Widespread
resistance by Plasmodium parasites to quinolone based antimalarials and decreased …
resistance by Plasmodium parasites to quinolone based antimalarials and decreased …
Elucidation of the anti-plasmodial activity of novel imidazole and oxazole compounds through computational and in vivo experimental approaches
TO Johnson, OE Adeyemi… - Journal of …, 2023 - Taylor & Francis
The development of resistance to conventional antimalarial therapies, along with the
unfavorable impact of the COVID-19 pandemic on the global malaria fight, necessitates a …
unfavorable impact of the COVID-19 pandemic on the global malaria fight, necessitates a …
ANTIPROTOZOAL AND ANTIDIABETIC ACTIVITIES OF SECONDARY METABOLITES ISOLATED FROM Vepris glandulosa
PO Ojuka - 2024 - repository.embuni.ac.ke
Protozoal infections, particularly malaria and neglected tropical diseases like kinetoplastid
diseases affect impoverished populations in tropical regions. Similarly, diabetes mellitus is …
diseases affect impoverished populations in tropical regions. Similarly, diabetes mellitus is …