[HTML][HTML] Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications …
KR LeFort, W Rungratanawanich, BJ Song - Cellular and Molecular Life …, 2024 - Springer
This review provides an update on recent findings from basic, translational, and clinical
studies on the molecular mechanisms of mitochondrial dysfunction and apoptosis of …
studies on the molecular mechanisms of mitochondrial dysfunction and apoptosis of …
Gut-microbiota prompt activation of natural killer cell on alcoholic liver disease
JA Eom, JJ Jeong, SH Han, GH Kwon, KJ Lee… - Gut …, 2023 - Taylor & Francis
The liver is rich in innate immune cells, such as natural killer (NK) cells, natural killer T cells,
and Kupffer cells associated with the gut microbiome. These immune cells are dysfunctional …
and Kupffer cells associated with the gut microbiome. These immune cells are dysfunctional …
[HTML][HTML] Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression
Alcohol-associated liver disease (ALD) is a substantial cause of morbidity and mortality
worldwide and represents a spectrum of liver injury beginning with hepatic steatosis (fatty …
worldwide and represents a spectrum of liver injury beginning with hepatic steatosis (fatty …
Nobiletin Protects Against Alcoholic Liver Disease in Mice via the BMAL1‐AKT‐Lipogenesis Pathway
X Li, R Zhuang, K Zhang, Y Zhang, Z Lu… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Alcoholic liver disease (ALD) is a global public health concern. Nobiletin, a
polymethoxyflavone abundant in citrus fruits, enhances circadian rhythms and ameliorates …
polymethoxyflavone abundant in citrus fruits, enhances circadian rhythms and ameliorates …
cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice
W Zhao, S Zhao, R Wei, Z Wang, F Zhang… - International …, 2024 - Elsevier
Chronic ethanol consumption is a prevalent condition in contemporary society and
exacerbates anxiety symptoms in healthy individuals. The activation of microglia, leading to …
exacerbates anxiety symptoms in healthy individuals. The activation of microglia, leading to …
[HTML][HTML] The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic target
M Wang, J Zhao, J Chen, T Long, M Xu, T Luo, Q Che… - PeerJ, 2024 - peerj.com
Liver disease is a common and serious threat to human health. The progression of liver
diseases is influenced by many physiologic processes, including oxidative stress …
diseases is influenced by many physiologic processes, including oxidative stress …
Direct effects of alcohol on gut‐epithelial barrier: Unraveling the disruption of physical and chemical barrier of the gut‐epithelial barrier that compromises the host …
CH Kuo, LL Wu, HP Chen, J Yu… - … of Gastroenterology and …, 2024 - Wiley Online Library
The development of alcohol‐associated diseases is multifactorial, mechanism of which
involves metabolic alteration, dysregulated immune response, and a perturbed intestinal …
involves metabolic alteration, dysregulated immune response, and a perturbed intestinal …
[HTML][HTML] Zonal expression of StARD1 and oxidative stress in alcoholic-related liver disease
R Fucho, E Solsona-Vilarrasa, S Torres, S Nuñez… - Journal of Lipid …, 2023 - ASBMB
Alcoholic-related liver disease (ALD) is one of the leading causes of chronic liver disease
and morbidity. Unfortunately, the pathogenesis of ALD is still incompletely understood …
and morbidity. Unfortunately, the pathogenesis of ALD is still incompletely understood …