[HTML][HTML] Lung neuroendocrine neoplasms: recent progress and persistent challenges

N Rekhtman - Modern Pathology, 2022 - Elsevier
This review summarizes key recent developments relevant to the pathologic diagnosis of
lung neuroendocrine neoplasms, including carcinoids, small cell lung carcinoma (SCLC) …

[HTML][HTML] Immunotherapy and targeting the tumor microenvironment: current place and new insights in primary pulmonary NUT carcinoma

X Li, H Shi, W Zhang, C Bai, M He, N Ta… - Frontiers in …, 2021 - frontiersin.org
Primary pulmonary nuclear protein of testis carcinoma is a rare and highly aggressive
malignant tumor. It accounts for approximately 0.22% of primary thoracic tumors and is little …

Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor‐1 and neuroendocrine markers

YP Hung, AL Chen, MS Taylor, TG Huynh… - …, 2021 - Wiley Online Library
Aims Nuclear protein in testis (NUT) carcinoma, an aggressive tumour driven by NUTM1
rearrangements, often involves the lung/mediastinum and shows squamous differentiation …

[HTML][HTML] The role of gene fusions in thymic epithelial tumors

AC Roden - Cancers, 2023 - mdpi.com
Simple Summary Thymic epithelial tumors (TET) are rare. Therefore, large studies,
specifically concerning genetic alterations, are difficult in these tumors and require multi …

NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion

M Chen, S Zhao, Z Liang, W Wang, P Zhou, L Jiang - Virchows Archiv, 2022 - Springer
Nuclear protein in testis (NUT) carcinoma (NC) is a rare aggressive tumor with a typical
NUTM1 gene rearrangement. Herein, we aimed to investigate the morphological and …

[HTML][HTML] Neuroendocrine and squamous cell phenotypes of NUT carcinoma are potential diagnostic pitfalls that discriminating it from mimickers, such as small cell and …

H Ninomiya, Y Sato, K Inamura, A Dobashi… - Diagnostic …, 2024 - Springer
Introduction NUT carcinoma is a rare cancer associated with a poor prognosis. Because of
its rarity, its diagnosis is challenging and is usually made by excluding other diagnoses …

[HTML][HTML] Diagnosis, treatment and prognosis of primary pulmonary NUT carcinoma: a literature review

J Yuan, Z Xu, Y Guo - Current Oncology, 2022 - mdpi.com
NUT carcinoma is a rare, highly lethal cancer characterized with the rearrangement of the
nuclear protein in testis (NUT) gene on chromosome 15q14, which primarily occurs in the …

Clinical and molecular features of pulmonary NUT carcinoma characterizes diverse responses to immunotherapy, with a pathologic complete response case

M Chen, X Chen, Y Zhang, W Wang, L Jiang - Journal of Cancer Research …, 2023 - Springer
Purpose Nuclear protein in testis (NUT) carcinoma is an uncommon malignant cancer
characterized by NUTM1 rearrangement. We aimed to investigate the clinicopathological …

[HTML][HTML] P63-negative pulmonary NUT carcinoma arising in the elderly: a case report

S Numakura, K Saito, N Motoi, T Mori, Y Saito… - Diagnostic …, 2020 - Springer
Background Pulmonary NUT carcinoma is rare, but lethal, thus, must not be overlooked. The
definitive diagnosis is made by a NUT monoclonal antibody or gene analysis, but these are …

[HTML][HTML] Case report: NUT carcinoma in an elderly woman with unique morphology and immunophenotype highlights a diagnostic pitfall

X Wei, X Teng, Y Zhang, M Cheng… - Translational Cancer …, 2022 - ncbi.nlm.nih.gov
Background NUT carcinoma (NC) is a rapidly progressing and rare neoplasm that primarily
affects younger patients and has a survival time of about 1 year. Most of these neoplasms …