Systemic amyloidosis is a rare protein misfolding and deposition disorder leading to
progressive organ failure. There are over 15 types of systemic amyloidosis, each caused by …

Hereditary amyloidogenic transthyretin (ATTRv) amyloidosis with polyneuropathy (also
known as familial amyloid polyneuropathy) is a condition with adult onset caused by …

Wild type transthyretin-derived amyloid (ATTRwt) is the major component of non-hereditary
transthyretin amyloidosis. Its accumulation in the heart of elderly patients is life threatening …

Transthyretin amyloidosis is a progressive and eventually fatal disease primarily
characterized by sensory, motor, and autonomic neuropathy and/or cardiomyopathy. Given …

Systemic ATTR amyloidosis is an increasingly important protein misfolding disease that is
provoked by the formation of amyloid fibrils from transthyretin protein. The pathological and …

Hereditary transthyretin amyloidosis (ATTRv) is a severe, adult-onset autosomal dominant
inherited systemic disease predominantly affecting the peripheral and autonomic nervous …

Hereditary systemic amyloidosis comprises a group of rare monogenic diseases inherited in
an autosomal dominant fashion. It is associated with mutations in genes encoding eight …

ATTR amyloidosis is caused by systemic deposition of transthyretin (TTR) and comprises
ATTRwt (wt for wild-type) amyloidosis, ATTRv (v for variant) amyloidosis, and acquired ATTR …

Objective To compare the natural history of familial transthyretin amyloid polyneuropathies
(FAP) due to the Val30Met, Ser77Tyr, and Ile107Val mutations in France with the classical …

Objective The objective of this study was to elucidate the natural history of late-onset
transthyretin Val30Met-associated familial amyloid polyneuropathy (FAP ATTR Val30Met) in …