Compared to intravitreal injection, subretinal injection has more direct effects on the
targeting cells in the subretinal space, which provides a new therapeutic method for …

The discovery of the CRISPR/Cas system and its development into a powerful genome
engineering tool have revolutionized the field of molecular biology and generated …

Retinal diseases, including age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are the leading causes of blindness in adults over the age of 50 years in …

Science of drug delivery has achieved tremendous milestones in the last few decades.
Emergence of novel drug delivery techniques and the most popular nanotechnology …

Glaucoma is one of the leading causes of blindness worldwide and will affect 79.6 million
people worldwide by 2020. It is caused by the progressive loss of retinal ganglion cells …

Inherited retinal diseases (IRDs) are a heterogeneous group of disorders causing
progressive loss of vision, affecting approximately one in 1000 people worldwide. Gene …

Recent advances in clinical ophthalmic imaging have enhanced patient care. However, the
ability to differentiate retinal neurons, such as retinal ganglion cells (RGCs), would advance …

Hereditary macular dystrophies (HMDs) are a genetically diverse group of disorders that
cause central vision loss due to photoreceptor and retinal pigment epithelium (RPE) …

Subretinal injection (SRI) is a widely used technique in retinal research and can be used to
deliver nucleic acids, small molecules, macromolecules, viruses, cells or biomaterials such …

Background: Gene therapy is a promising approach for the treatment of various diseases,
including cancer, hereditary disorders, and some viral infections. The development of …