Adenoviruses: update on structure and function

WC Russell - Journal of General Virology, 2009 - microbiologyresearch.org
Adenoviruses have been studied intensively for over 50 years as models of virus–cell
interactions and latterly as gene vectors. With the advent of more sophisticated structural …

Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds

J He, L Yu, X Lin, X Liu, Y Zhang, F Yang, W Deng - Viruses, 2022 - mdpi.com
Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …

Intracellular trafficking of nonviral vectors

LK Medina-Kauwe, J Xie, S Hamm-Alvarez - Gene therapy, 2005 - nature.com
Nonviral vectors continue to be attractive alternatives to viruses due to their low toxicity and
immunogenicity, lack of pathogenicity, and ease of pharmacologic production. However …

The structure of the human adenovirus 2 penton

C Zubieta, G Schoehn, J Chroboczek, S Cusack - Molecular cell, 2005 - cell.com
The adenovirus penton, a noncovalent complex of the pentameric penton base and trimeric
fiber proteins, comprises the vertices of the adenovirus capsid and contains all necessary …

The adenovirus dodecahedron: beyond the platonic story

S Besson, C Vragniau, E Vassal-Stermann, MC Dagher… - Viruses, 2020 - mdpi.com
Many geometric forms are found in nature, some of them adhering to mathematical laws or
amazing aesthetic rules. One of the best-known examples in microbiology is the icosahedral …

A proliferation‐inducing ligand–mediated anti‐inflammatory response of astrocytes in multiple sclerosis

L Baert, M Benkhoucha, N Popa, MC Ahmed… - Annals of …, 2019 - Wiley Online Library
Objective The two related tumor necrosis factor members a proliferation‐inducing ligand
(APRIL) and B‐cell activation factor (BAFF) are currently targeted in autoimmune diseases …

Adenovirus dodecahedron, as a drug delivery vector

M Zochowska, A Paca, G Schoehn, JP Andrieu… - PLoS …, 2009 - journals.plos.org
Background Bleomycin (BLM) is an anticancer antibiotic used in many cancer regimens. Its
utility is limited by systemic toxicity and dose-dependent pneumonitis able to progress to …

Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma

M Zochowska, AC Piguet, J Jemielity… - … , Biology and Medicine, 2015 - Elsevier
Adenovirus dodecahedron (Dd), a nanoparticulate proteinaceous biodegradable virus-like
particle (VLP), was used as a vector for delivery of an oncogene inhibitor to hepatocellular …

The good the bad and the ugly of glycosaminoglycans in tissue engineering applications

BI Ayerst, CLR Merry, AJ Day - Pharmaceuticals, 2017 - mdpi.com
High sulfation, low cost, and the status of heparin as an already FDA-and EMA-approved
product, mean that its inclusion in tissue engineering (TE) strategies is becoming …

[HTML][HTML] Involvement of glycosaminoglycans in the attachment of pneumococci to nasopharyngeal epithelial cells

ELGM Tonnaer, TG Hafmans, TH Van Kuppevelt… - Microbes and …, 2006 - Elsevier
Streptococcus pneumoniae is a major bacterial pathogen involved in the development of
otitis media. The pathogenic mechanisms of this middle ear disease, including the bacterial …