[HTML][HTML] Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

Ó Monroig, AC Shu-Chien, N Kabeya, DR Tocher… - Progress in lipid …, 2022 - Elsevier
Marine ecosystems are rich in “omega-3” long-chain (C 20-24) polyunsaturated fatty acids
(LC-PUFA). Their production has been historically accepted to derive mostly from marine …

Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire

LFC Castro, DR Tocher, O Monroig - Progress in lipid research, 2016 - Elsevier
Long-chain polyunsaturated fatty acids (LC-PUFA) are major components of complex lipid
molecules and are also involved in numerous critical biological processes. Studies …

Omega-3 long-chain polyunsaturated fatty acids and aquaculture in perspective

DR Tocher - Aquaculture, 2015 - Elsevier
In the 40 years since the essentiality of polyunsaturated fatty acids (PUFA) in fish was first
established by determining quantitative requirements for 18: 3n− 3 and 18: 2n− 6 in rainbow …

Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish

D Xie, C Chen, Y Dong, C You, S Wang… - Progress in Lipid …, 2021 - Elsevier
Abstract Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C 20-24),
including eicosapentaenoic acid (EPA, 20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n …

[图书][B] Fish oil replacement and alternative lipid sources in aquaculture feeds

GM Turchini, WK Ng, DR Tocher - 2010 - taylorfrancis.com
Experts are predicting that demand for marine fish oil will soon outstrip supply, creating
extreme urgency within the global aquafeed industry to find viable alternatives. Fish Oil …

Desaturases and elongases involved in polyunsaturated fatty acid biosynthesis in aquatic invertebrates: a comprehensive review

Ó Monroig, N Kabeya - Fisheries Science, 2018 - Springer
Invertebrates represent a large proportion of the biomass in aquatic ecosystems, particularly
in the ocean. In recent years, invertebrates have been well-consolidated models in …

Characterization and modulation of gene expression and enzymatic activity of delta-6 desaturase in teleosts: A review

M Vagner, E Santigosa - Aquaculture, 2011 - Elsevier
There is currently considerable interest in understanding how the biosynthetic pathways of
highly unsaturated fatty acids (HUFA) are regulated in fish. The aim is to know if it is possible …

CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target …

AK Datsomor, N Zic, K Li, RE Olsen, Y Jin, JO Vik… - Scientific reports, 2019 - nature.com
Atlantic salmon can synthesize polyunsaturated fatty acids (PUFAs), such as
eicosapentaenoic acid (20: 5n-3), arachidonic acid (20: 4n-6) and docosahexaenoic acid …

Functional Desaturase Fads1 (Δ5) and Fads2 (Δ6) Orthologues Evolved before the Origin of Jawed Vertebrates

LFC Castro, O Monroig, MJ Leaver, J Wilson, I Cunha… - PloS one, 2012 - journals.plos.org
Long-chain polyunsaturated fatty acids (LC-PUFAs) such as arachidonic (ARA),
eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are essential components of …

Nutritional programming in fishes: insights from mammalian studies

Z Hou, LA Fuiman - Reviews in Fish Biology and Fisheries, 2020 - Springer
Epidemiological evidence and subsequent studies using mammalian models have
established a strong correlation between suboptimal nutritional status during early life and …