Objective: Elevated levels of serum Nε-carboxymethyllysine (CML), a well-known advanced
glycation end-product (AGE), were observed in patients with inflammation or osteoporosis …

The passage number of cells refers to the number of subculturing processes that the cells
have undergone. The effect of passage number on morphological and phenotypical …

Objective: Advanced glycation end products (AGEs), such as Nε-(carboxymethyl)-lysine
(CML), pentosidine are elevated in serum of osteoporotic patients, which may possibly be …

The non-enzymatic reaction between the reactive carbonyl group of reducing sugars and the
free amino group of protein or nucleic acid produces a harmful heterogeneous molecule …

Aim: Bone remodeling by which mature bone tissue is removed by osteoclast and new bone
tissue is formed by osteoblast, is important to maintain bone mass and quality. Imbalanced …

Bone remodeling (or bone homeostasis) is a lifelong process that serves to regulate bone
structure to meet changing mechanical requirements and to repair micro damages or …

Objectives: Protein structure and function is continuously demolished by nonenzymatic
glycation and thereby produce advanced glycation end products (AGE). Therefore, the …

Bone remodeling (or bone homeostasis) is a lifelong process that serves to regulate bone
structure to meet changing mechanical requirements and to repair micro damages or …

Advanced glycation end products (AGEs) are formed by proteins or lipids and carbohydrates
or the degradation products of carbohydrates under the non-enzymatic reactions …